Beneficial effect of beetroot or spinaze consumption in mitochondrial myopathy patients.
- Conditions
- mitochondrial myopathy
- Registration Number
- NL-OMON26686
- Lead Sponsor
- Eindhoven University of TechnologyErasmus Medical CenterMaxima Medical CenterUniverisity Medical Centre MaastrichtUniversity Medical Center Groningen
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
1. Diagnosis mitochondrial myopathy;
2. Age 18+.
Exclusion Criteria
1. Pacemaker / ICS or other contra indication for MRI;
2. Claustrophobia;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Steady state oxygen consumption at 50%Wmax;<br /><br>2. In vivo mitochondrial function (31P MRS);<br /><br>3. In vitro mitochondrial function (state 3, 4, U respiration).
- Secondary Outcome Measures
Name Time Method 1. mtDNA copy number;<br /><br>2. C1, C2, C3, C4, F1F0ATPase, ANT content;<br /><br>3. Muscle fiber type composition.