Methoxyflurane versus Nitrous Oxide: Which provides better pain relief in patients undergoing Trans-Vaginal Oocyte Retrieval (TVOR) with conscious sedation?
Phase 4
Recruiting
- Conditions
- Trans vaginal oocyte retrievalReproductive Health and Childbirth - Fertility including in vitro fertilisationAnaesthesiology - Pain management
- Registration Number
- ACTRN12621000941864
- Lead Sponsor
- Dr Aine McNally Bogue
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 86
Inclusion Criteria
Women undergoing Transvaginal Oocyte Retrieval (TVOR) at The Fertility Centre Liverpool (TFCL) who have consented to partake in the study.
Exclusion Criteria
Women who have had previous adverse reaction or hypersensitivity to either agent, patients with contraindications to either medication including significant respiratory, renal or hepatic compromise, recent eye surgery using intraocular gas, patients who have taken part in the study previously and patients who request specific agents.
Of note, at TFC, as a low cost, low risk clinic our protocol dictates we do not treat patients with significant co morbidities or severe endometriosis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain measured on 100mm VAS[Immediately post procedure and 15 minutes post procedure]
- Secondary Outcome Measures
Name Time Method Side effects experienced will be assessed by a study specific patient questionnaire. [15 minutes Post procedure];Oocyte number, which will be recorded on a study specific data collection sheet once the final count is determined by the embryologist. [In theatre, once the final number is determined by the embryologist, usually within 15 minutes post procedure];Fertilization rate, which will be assessed via data linkage to patients medical records[One week post procedure];Blastulation rate which will be assessed via data linkage to patients medical record[One week post procedure];Clinical pregnancy rate which will be assessed via data linkage to patients medical record[6 weeks post procedure];Length of procedure (from first puncture to scanner withdrawal) which will be recorded on a study specific data proforma[Immediately post procedure]