The efficacy of inhaled methoxyflurane for pain control of selective nerve root block injection for lumbar radiculopathy: A randomized, placebo controlled trial

Phase 4

Completed

• Conditions: umbar HNP/spinal stenosis with Radiculopathy; Lumbar HNP/spinal stenosis with Radiculopathy

• Registration Number: TCTR20220706001
• Lead Sponsor: Faculty of Medicine Thammasat University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-06
• Study Completion: 2024-01-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patient diagnosed Lumbar HNP/spinal stenosis with Radiculopathy
(1-3 Level , Dx by MRI ,conservative > 3 months)
Age >18 years
Understand the protocol and volunteered to join the study

Exclusion Criteria

Cannot undertaken SNRB injection/not co-operate to use Inhaled methoxyflurane
History of Traumatic back pain , Spinal surgery , Active infection
Severe degenerative spine
Pregnancy /Lactation
Allergy to study drugs (Inhaled methoxyflurane & other drugs in standard order)
Renal insufficiency (Creatinine clearance <30ml/min)
History of cardiovascular instability , lung or respiratory impairment , stroke or intracranial surgery
Abnormal liver function (2.5xULN)
Established malignant hyperthermia
Last administration of methoxyflurane

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain during operation Visual analogue scale

Secondary Outcome Measures

Name	Time	Method
pain post-use inhaled methoxyflurane ( at 0 min ,30 min , 60 min , 90 min , 120 min ) Visual analogue scale,Adverse effect at 2 weeks after end of the intervention adverse effect choices,Satisfactory during operation Satisfactory score