Pain relief of methoxyflurane in patients with burns

Phase 1

• Conditions: Pain after burns; MedDRA version: 20.0Level: LLTClassification code 10006634Term: BurnSystem Organ Class: 100000004863; Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]

• Registration Number: EUCTR2020-005865-14-DK
• Lead Sponsor: Rigshospitalet

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-12-08
• Last Update Posted: 17 May 2021

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Burns with need for change of wound dressing. Age at least 18 years, able to provide informed consent.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 25
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 5

Exclusion Criteria

Renal failure (GFR below 60 ml/min)
Liver failure
Liver toxicity after exposure to halogenated inhalational anaesthetics
Genetic predisposition for malignant hyperthermia.
Current treatment with isoniazide, gentamicine, tetracycline, colistien or amphotericine B.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified