NCT00875732已完成不适用
CHOosing the rIght paCing Mode in Heart failurE : Should Heart Failure Patients With Bradycardia Receive Biventricular Pacemakers Rather Than Conventional Pacemakers?
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 2
- 主要终点
- 6 minute hall walk test
研究概览
简要总结
The aim of the study is to see if biventricular pacemakers offer any advantage over conventional pacemakers in patients with heart failure who require pacemakers. The endpoints will be the 6 minute walking distance along with markers of cardiovascular function.
The investigators' hypothesis is that biventricular pacing is preferable to conventional pacing in these heart failure patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Left ventricular systolic dysfunction.
- •Atrio-ventricular node disease.
- •Anticipated to be more than 40% paced, (including patients in permanent atrial fibrillation).
- •Ability to walk independently (walking aid permitted).
排除标准
- •Patients meeting criteria for CRT by current guidelines will be excluded.
- •Life expectancy less than12 months.
- •Inability to walk independently.
- •Patients not likely to be compliant with follow-up.
- •Bradyarrhythmia due with sino-atrial disease only.
结局指标
主要结局
6 minute hall walk test
时间窗: Baseline, 3, 6, 9 and 12 months
次要结局
- Cardiac Output(Baseline, 3, 6, 9 and 12 months)
- Endothelial Function(Baseline, 3, 6, 9 and 12 months)
研究者
AChoy
Dr. Anna Maria Choy
University of Dundee
研究点 (2)
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