Early Diagnosis of Asthma in Young Children
Not Applicable
Completed
- Conditions
- Asthma
- Interventions
- Drug: beclomethasondipropionate
- Registration Number
- NCT00422747
- Lead Sponsor
- Maastricht University Medical Center
- Brief Summary
The overall aim of the study is an early asthma diagnosis in young children by the use of non-invasive biomarkers of airway inflammation /oxidative stress in exhaled air, and early lung function measurements
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 202
Inclusion Criteria
- Children aged 2-3 years, with recurrent respiratory symptoms suggestive of asthma
- Children aged 2-3 years, with no or minor respiratory symptoms
Exclusion Criteria
- Mental retardation
- Cardiac anomalies
- Congenital malformations
- Other diseases of the lungs/airways
- Chronic systemic inflammatory diseases like M. Crohn
- The inability to perform lung function measurements and/or exhaled air collection
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description beclomethasondipropionate beclomethasondipropionate 2 x 100 ug dd for two months, via aerochamber
- Primary Outcome Measures
Name Time Method - definite asthma diagnosis - biomarkers in exhaled breath 6 years of age
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Maastricht University Medical Centre
🇳🇱Maastricht, Limburg, Netherlands