Early Diagnosis of Asthma in Young Children

Not Applicable

Completed

• Conditions: Asthma
• Interventions: Drug: beclomethasondipropionate

• Registration Number: NCT00422747
• Lead Sponsor: Maastricht University Medical Center

Brief Summary

The overall aim of the study is an early asthma diagnosis in young children by the use of non-invasive biomarkers of airway inflammation /oxidative stress in exhaled air, and early lung function measurements

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2007-01-15
• Study First Submitted QC: 2007-01-15
• Study First Posted: 2007-01-17
• Study Start: 2007-04
• Primary Completion: 2011-06
• Study Completion: 2012-08
• Status Verified: 2013-06
• Last Update Submitted: 2013-06-17
• Last Update Posted: 2013-06-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 202

Inclusion Criteria

• Children aged 2-3 years, with recurrent respiratory symptoms suggestive of asthma
• Children aged 2-3 years, with no or minor respiratory symptoms

Exclusion Criteria

• Mental retardation
• Cardiac anomalies
• Congenital malformations
• Other diseases of the lungs/airways
• Chronic systemic inflammatory diseases like M. Crohn
• The inability to perform lung function measurements and/or exhaled air collection

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
beclomethasondipropionate	beclomethasondipropionate	2 x 100 ug dd for two months, via aerochamber

Primary Outcome Measures

Name	Time	Method
- definite asthma diagnosis - biomarkers in exhaled breath	6 years of age

Trial Locations

Locations (1)

Maastricht University Medical Centre; 🇳🇱 Maastricht, Limburg, Netherlands