Pediatric Asthma Non-invasive Diagnostic Approaches

Recruiting

• Conditions: asthma; chronic airway disease; 10001708; 10006436

• Registration Number: NL-OMON55765
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

- Between 6-17 years of age
- Doctor*s diagnosis of asthma
- Treated on asthma GINA treatment step 3 or higher
- Signed informed consent from parents (guardians) and children (when
applicable)
- Dutch speaking

Exclusion Criteria

Serious lung disease other than asthma (cystic fibrosis, primary ciliary
dyskinesia, congenital lung disorders, severe immune disorders).

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Differences in clinical characteristics and biomarker profiles between children<br /><br>that remain difficult to treat upon standardized clinical care (based on<br /><br>symptoms, exacerbations and lung function) and children that are controlled. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>reduction in number of exacerbations<br /><br>improvement in severe asthma questionnaire score<br /><br>improvement in fatigue<br /><br>unsupervised cluster analyses on the -omics data</p><br>