Genetically determined brain abnormalities in Down’s Syndrome.- towards a treatment: A randomised, single-blind, placebo-controlled trial of lithium carbonate in Down’s Syndrome (DownsLit). - Downs Syndrome Lithium Trial (DownsLit)

King's College London0 sites34 target enrollmentJuly 9, 2009

Overview

No summary available.

Registry

who.int

Start Date

July 9, 2009

End Date

TBD

Last Updated

7 years ago

Study Type

Interventional clinical trial of medicinal product

Sex

All

Sponsor

•Individuals with Down Syndrome
•Over the age of 18 years
•Able to provide informed consent or have a legal representative to consent on their behalf if they lack capacity
•Able to communicate with the investigator and to comply with requirements of the study
•Has carer support
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1\.2 Adults (18\-64 years) yes
•F.1\.2\.1 Number of subjects for this age range 34
•F.1\.3 Elderly (\>\=65 years) no

•Individuals with contraindications to lithium treatment
•Individuals with contraindications to undergoing a magnetic resonance scan
•Non\-compliance with taking of the tablets between baseline and the 4\-week assessment
•Treatment with lithium within the last 6 months
•Evidence of dementia