Genetically determined brain abnormalities in Down's syndrome - towards a treatment: a randomised, single-blind, placebo-controlled trial of lithium carbonate in Down's syndrome

King's College London (UK)0 个研究点目标入组 19 人开始时间: 2009年8月19日最近更新: 2019年6月17日

适应症

试验速览

暂无简介。

•1. Individuals with Down's syndrome
•2. Over the age of 18 years, either sex
•3. Able to provide informed consent for themselves or have a representative to provide proxy consent on their behalf if they lack capacity
•4. Able to communicate with the investigator and to comply with requirements of the study
•5. Has carer support

•1. Individuals with contraindications to lithium treatment
•2. Individuals with contraindications to undergoing a magnetic resonance scan
•3. Non-compliance with taking of the tablets between baseline and the final assessment
•4. Treatment with lithium within the last 6 months
•5. Evidence of dementia
•6. Evidence of renal, thyroid or cardiac disease that would contraindicate taking lithium
•7. Pregnancy

发起方

King's College London (UK)