Magnetic resonance imaging in patients with chronic total occlusions of the coronary arteries
Not Applicable
- Conditions
- Chronic total coronary occlusion (CTO)Circulatory System
- Registration Number
- ISRCTN33203221
- Lead Sponsor
- Heart Clinic Ulm
- Brief Summary
2023 Interim results article in https://doi.org/10.1007/s10554-023-02916-9 Baseline angina burden predicts quality of life and functional improvement in patients with viable myocardium treated for chronic total occlusion (added 13/07/2023)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
All patients with angiographic proven CTO
Exclusion Criteria
1. Myocardial infarctions in the last three months
2. Instable angina
3. Contraindications for CMR, gadolinium-based contrast agents or the intravenous administration of adenosine
4. Impaired renal function (glomerular filtration rate < 30ml/min)
5. Inability to give written informed consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Symptom burden with angina pectoris in repeated surveys using the Seattle Angina questionnaire (SAQ) at baseline and 3, 12, 24 and 36 months
- Secondary Outcome Measures
Name Time Method eft and right ventricular ejection fractions, strain measurements and first-pass perfusion measured using a CMR scan at baseline and 3 up to 6 months after