The Role of Computed Tomography in the Phenotyping of COPD Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Identifying the different phenotypes of COPD using HRCT
研究概览
简要总结
Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease that is characterized by respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities usually caused by significant exposure to noxious particles or gases. the CT was used for classification of COPD patients into different phenotypes: phenotype A that has minimal emphysema with or without airway disease, phenotype E that has emphysema without airway disease, and finally phenotype M as a mixed form. The investigators aimed to to identify the phenotypes of COPD using radiologic data obtained by computed tomography. Moreover, this study will be designed to answer the questions about possible correlation between pulmonary function parameters and CT.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All stable COPD patients that lastly confirmed to have the disease based on spirometry and past clinical history according to GOLD (2022).
- •Age above 18 years.
排除标准
- •COPD patients associated with other chest diseases as collapse
- •COPD patients associated with consolidation
- •COPD patients unable to perform spirometry
结局指标
主要结局
Identifying the different phenotypes of COPD using HRCT
时间窗: one month
Identifying the different phenotypes of COPD using HRCT. moreover, to identify whether there is a possible correlation between CT phenotypes and FEV1, FVC or FEV1/FVC.
次要结局
未报告次要终点
研究者
Islam Galal Sayed
Professor
Aswan University
