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临床试验/NCT05747235
NCT05747235已完成不适用

The Role of Computed Tomography in the Phenotyping of COPD Patients

Aswan University1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2022年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
50
试验地点
1
主要终点
Identifying the different phenotypes of COPD using HRCT

研究概览

简要总结

Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease that is characterized by respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities usually caused by significant exposure to noxious particles or gases. the CT was used for classification of COPD patients into different phenotypes: phenotype A that has minimal emphysema with or without airway disease, phenotype E that has emphysema without airway disease, and finally phenotype M as a mixed form. The investigators aimed to to identify the phenotypes of COPD using radiologic data obtained by computed tomography. Moreover, this study will be designed to answer the questions about possible correlation between pulmonary function parameters and CT.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All stable COPD patients that lastly confirmed to have the disease based on spirometry and past clinical history according to GOLD (2022).
  • Age above 18 years.

排除标准

  • COPD patients associated with other chest diseases as collapse
  • COPD patients associated with consolidation
  • COPD patients unable to perform spirometry

结局指标

主要结局

Identifying the different phenotypes of COPD using HRCT

时间窗: one month

Identifying the different phenotypes of COPD using HRCT. moreover, to identify whether there is a possible correlation between CT phenotypes and FEV1, FVC or FEV1/FVC.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Islam Galal Sayed

Professor

Aswan University

研究点 (1)

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