Evaluation of the effects of citalopram and doxepin in patients with chronic obstructive pulmonary disease

Phase 3

• Conditions: Condition 1: Depression. Condition 2: Anxiety. Condition 3: Chronic obstructive pulmonary disease.; Other depressive episodes; Anxiety disorder due to known physiological condition; Other chronic obstructive pulmonary disease; F32.8; F06.4

• Registration Number: IRCT20161023030452N2
• Lead Sponsor: Zanjan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 June 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

Age over 40 years
Having any class of COPD with any severity
Having symptoms of depression and anxiety
Patients with stable COPD so that their disease status does not change from day to day and are under constant treatment and there is no change in the type of treatment

Exclusion Criteria

Those whose illness has worsened recently (one week from the start of the study) or while studying
Patients with severe dementia, severe cognitive impairment, end-stage cancer, and mental illness, including schizophrenia, suicidal ideation, and more
Patients who have recently (two weeks after the start of the study) taken monoamine oxidase inhibitors or those who are taking these medications
Patients whose ECG shows long QT intervals
Pregnant or lactating women
Patients with severe liver, kidney, cardiovascular and motor diseases
Patients with uncontrollable epilepsy
Patients with a history of intolerance to antidepressants

Study & Design

• Study Type: interventional
• Study Design: Not specified