Comparative Efficacy of Greater Occipital Nerve Blockade and Sphenopalatine Ganglion Blockade in Patients With Episodic Migraine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Degree of headache intensity
研究概览
简要总结
This study compares the effectiveness of greater occipital nerve blockade and sphenopalatine ganglion blockade in reducing headache intensity, duration, frequency, and disability in patients with episodic migraine.
详细描述
Migraine is a chronic neurological disorder characterized by recurrent headaches, affecting millions globally. Peripheral nerve blocks such as Greater Occipital Nerve (GON) and Sphenopalatine Ganglion (SPG) blockade have emerged as promising non-pharmacologic treatments.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18-65 years.
- •Both sexes.
- •Diagnosed with episodic migraine per the International Classification of Headache Disorders, 3rd edition (ICHD-3).
- •Failure to achieve adequate relief with at least one prophylactic migraine treatment.
排除标准
- •Chronic migraine (≥15 headache days per month).
- •History of nerve blocks within the last 6 months.
- •Known allergy to anesthetic agents.
- •Pregnancy or lactation.
- •Active psychiatric conditions affecting compliance.
研究组 & 干预措施
Greater occipital nerve blockade group
Patients will receive greater occipital nerve blockade using 2 mL of 2% lidocaine at the medial one-third of the line between the occipital protuberance and mastoid process.
干预措施: Greater occipital nerve blockade (Other)
Sphenopalatine ganglion blockade group
Patients will receive greater sphenopalatine ganglion blockade using 2 mL of 2% lidocaine using a transnasal approach with a cotton swab inserted along the superior middle turbinate to the posterior nasopharyngeal wall.
干预措施: Sphenopalatine ganglion blockade (Other)
结局指标
主要结局
Degree of headache intensity
时间窗: 3 months post-procedure
Reduction in headache intensity will be recorded using numeric rating scale (NRS). Each patient will be instructed about pain assessment with NRS score. NRS (0 represents "no pain" while 10 represents "the worst pain imaginable").
次要结局
- Migraine disability assessment score(3 months post-procedure)
- Headache duration(3 months post-procedure)
- Headache frequency(3 months post-procedure)
研究者
Ahmed Omar Twaisy
Lecturer of Anesthesia and Intensive Care, Faculty of Medicine, New Valley University, Egypt.
New Valley University