Greater Occipital and Supraorbital Nerve Blockade For The Preventive Treatment of Migraine
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 103
- 主要终点
- Change of Frequency of Headache
研究概览
简要总结
The investigators aimed to evaluate the efficacy of greater occipital nerve and supraorbital nerve blockade with local anesthetics for the preventive treatment of migraine without aura.
详细描述
A mixture of 1 ml 2% lidocaine and 0.9% 1 ml saline was injected bilaterally to GON and SON in the blockade patients. Placebo patients received 2 ml 0.9% saline in the same way. Patients were blinded to kind of injection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Lack of benefits 1 year from preventive treatment or intolerance to their treatments.
- •18 ≥ years old
- •Migraine without aura for more than 1 year, minimum of two or more migraine attacks per month.
排除标准
- •Patients with any chronic illness, medication overuse headache, a history of cranial and cervical surgery
- •Allergies to local anesthetics
- •Hemorrhagic diathesis
- •Alcohol or drug abuse
结局指标
主要结局
Change of Frequency of Headache
时间窗: Patients were followed up from baseline to 2 months after first injection.
Number of headache days in a month. Scores from both months were averaged. Minimum=0 Maximum=30. Lower scores mean a better outcome.
Change of Severity of Headache
时间窗: Patients were followed up for 2 months from baseline after first injection.
Mean visual analog scale (VAS) scores. Scores from both months were avareged. Minimum=0 Maximum=10. Lower scores mean a better outcome
次要结局
未报告次要终点
研究者
Cem Bölük
Medical Doctor
Dr. Lutfi Kirdar Kartal Training and Research Hospital