Response of Metabolic Syndrome and Sexual Dysfunction to Lifestyle Changes in Men With Psoriasis

Not Applicable

Recruiting

• Conditions: Psoriasis; Metabolic Syndrome; Erectile Dysfunction

• Registration Number: NCT05632042
• Lead Sponsor: Cairo University

Brief Summary

complaint of sexual dysfunction and metabolic syndrome are highly reported in men with psoriasis

Detailed Description

erectile dysfunction (ED) psoriatic men with metabolic syndrome (number of the patients will be 60) will assigned to study group (group = 30 patients) that will receive lifestyle changes (12 weeks of low calorie diet and moderate-intensity walking on treadmill, the walking duration will be 40 minutes, the walking will be three times per week) or control group (group=30 patients) that will receive no lifestyle changes/modifications.

Study Timeline

• Study Start: 2022-10-16
• Status Verified: 2022-11
• Study First Submitted: 2022-11-20
• Study First Submitted QC: 2022-11-20
• Last Update Submitted: 2022-11-20
• Study First Posted: 2022-11-30
• Last Update Posted: 2022-11-30
• Primary Completion: 2023-04-16
• Study Completion: 2023-04-16

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Male
• Target Recruitment: 60

Inclusion Criteria

• psoriatic married men with metabolic syndrome and erectile dysfunction

Exclusion Criteria

• patients with heart, respiratory, other autoimmune problems

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
International Index of Erectile Function	It will be measured after 12-week intervention	Arabic version of this 5-item questionnaire will used to assess erectile function/dysfunction

Secondary Outcome Measures

Name	Time	Method
psoriasis area and severity index	It will be measured after 12-week intervention	it is a tool used to measure the severity and extent of psoriasis.
body mass index	It will be measured after 12-week intervention	patients will be assessed with empty bowel and bladder
systolic blood pressure	It will be measured after 12-week intervention	it will be measured using sphygmomanometer
triglycerides	It will be measured after 12-week intervention	it will be measured in serum
diastolic blood presure	It will be measured after 12-week intervention	it will be measured using sphygmomanometer
waist circumference	It will be measured after 12-week intervention	it will be measured by in elastic tape
high density lipoprotein	It will be measured after 12-week intervention	it will be measured in serum
blood glucose	It will be measured after 12-week intervention	it will be measured in fasting status

Trial Locations

Locations (1)

Cairo Unoversity; 🇪🇬 Giza, Egypt