Photosensitivity and Keratinocyte Carcinomas amongst Thai Patients receiving Voriconazole and Posaconazole, an ambispective cohort study: phase 1

• Conditions: Photosensitivity amongst Thai patients receiving voriconazole or posaconazoleSkin cancer amongst Thai patients receiving voriconazole or posaconazole; voriconazole, posaconazole, photosensitivity, squamous cell carcinoma

• Registration Number: TCTR20230210006
• Lead Sponsor: Graduate Affairs, Faculty of Medicine, Chulalongkorn Univerisity

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-02-10
• Study Completion: 2023-08-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: nknown
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1.Patients receiving voriconazole or posaconazole at King Chulalongkorn Memorial Hospital more than 7 days during 2012-2022
2.Controls group, age, sex, Fitzpatrick skin type, and organ transplant profile-matched controls receving fluconazole or itraconazole at King Chulalongkorn Memorial Hospital
during 2012-2022

Exclusion Criteria

1.No data regarding voriconazole level available
2.Clinically unstable patient and unable to follow investigator's appointment

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of photosensitivity and skin cancer one time Ratio of patients with interested outcome and all patients in the study

Secondary Outcome Measures

Name	Time	Method
Phototesting result amongst patient receiving voriconazole or posaconazole one time Phototesting,Risk factors of photosensitivity and skin cancer amongst patient receiving voriconazole and posaconazole One time Patient reported history using a questionnaire interview