CTRI/2022/07/044455Not yet recruitingNot Applicable
Evaluation of postoperative analgesic effect of intraperitoneal instillation of 0.125% levobupivacaine + 1 μg/kg dexmedetomidine or 0.2% ropivacaine +1 μg/kg dexmedetomidine after laparoscopic cholecystectomy.
JLN medical college Ajmer1 site in 1 country60 target enrollmentStarted: May 8, 2022Last updated:
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- 1. Duration of post operative analgesia.
Study Overview
Brief Summary
We aimed to conduct a study to evaluate postoperative analgesic efficacy of intraperitoneal instillation of levobupivacaine + dexmedetomidine or ropivacaine + dexmedetomidine in patients undergoing laparoscopic cholecystectomy.
Study Design
- Study Type
- Interventional
- Allocation
- Computer generated randomization
- Masking
- Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •1.Patient belonging to ASA I and II 2.Gall bladder calculi.
Exclusion Criteria
- •ASA grade III and above.
- •age <18 years and >60 years.
- •patients with severe systemic disease like IDDM, uncontrolled hypertension, kidney and liver disease, severe respiratory disease.
- •seizure disorder.
- •CAD or recent history of MI.
- •Anticipated difficult intubation.
- •body weight >100kg or obese.
- •pregnant and lactating women.
- •patient of psychiatric disorder and sleep disorders.
- •10.hypersensitivity to study drugs.
- •11.conversion of laparoscopic cholecystectomy to open cholecystectomy.
Outcomes
Primary Outcomes
1. Duration of post operative analgesia.
Time Frame: 1. Duration of post operative analgesia at 0,1,2,4,6,8,10,12,24 hours.
Secondary Outcomes
- 1.total rescue analgesic required in 24 hours.(2. hemodyanamic changes.)
Investigators
Study Sites (1)
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