To compare the effects of two drug groups, levobupivacaine and dexmedetomidine with ropivacaine and dexmedetomidine for intraperitoneal injection after laparoscopic gall bladder removal.

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/07/044455
• Lead Sponsor: JLN medical college Ajmer

Brief Summary

We aimed to conduct a study to evaluate postoperative analgesic efficacy of intraperitoneal instillation of levobupivacaine + dexmedetomidine or ropivacaine + dexmedetomidine in patients undergoing laparoscopic cholecystectomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-08
• Last Update Posted: 2022-07-27

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1.Patient belonging to ASA I and II 2.Gall bladder calculi.

Exclusion Criteria

• ASA grade III and above.
• age <18 years and >60 years.
• patients with severe systemic disease like IDDM, uncontrolled hypertension, kidney and liver disease, severe respiratory disease.
• seizure disorder.
• CAD or recent history of MI.
• Anticipated difficult intubation.
• body weight >100kg or obese.
• pregnant and lactating women.
• patient of psychiatric disorder and sleep disorders.
• 10.hypersensitivity to study drugs.
• 11.conversion of laparoscopic cholecystectomy to open cholecystectomy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Duration of post operative analgesia.	1. Duration of post operative analgesia at 0,1,2,4,6,8,10,12,24 hours.

Secondary Outcome Measures

Name	Time	Method
1.total rescue analgesic required in 24 hours.	2. hemodyanamic changes.

Trial Locations

Locations (1)

JLN medical college Ajmer; 🇮🇳 Ajmer, RAJASTHAN, India

JLN medical college Ajmer

🇮🇳Ajmer, RAJASTHAN, India

Dr Vinod kumar saini

Principal investigator

09929628371

vinodsn332@gmail.com