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Clinical Trials/NCT02638480
NCT02638480
Unknown
Not Applicable

A Prospective Randomized Trial to Examine the Effectiveness of KneeMD on Flexion Contracture in Total Knee Arthroplasty Patients

Anne Arundel Health System Research Institute1 site in 1 country100 target enrollmentNovember 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Flexion Contracture
Sponsor
Anne Arundel Health System Research Institute
Enrollment
100
Locations
1
Primary Endpoint
AROM
Last Updated
7 years ago

Overview

Brief Summary

The purpose of this study is to evaluate the effect of the KneeMD subject-controlled knee rehabilitation device on the incidence of postoperative flexion contracture.

Detailed Description

Postoperative flexion contracture (FC), defined as \>10°, is the most common disabling early complication of primary total knee replacement (TKR) surgery, affecting up to 6% of all subjects. A knee flexion of 65° is required to walk, 70° is needed to lift an object from the floor, 85° to climb stairs, 95° for optimal sitting and standing, and 105° to tie shoelaces. With growing subject and physician expectations for function and range of motion (ROM) after surgery, FC complications have become an early measure of success in TKR surgery. The purpose of this study is to evaluate the effect of the KneeMD subject-controlled knee rehabilitation device on the incidence of postoperative FC. The primary endpoints are the preoperative change in active range of motion (AROM) and the incidence of postoperative FC at 2 weeks. Secondary endpoints include the change in AROM in subjects with postoperative FC.

Registry
clinicaltrials.gov
Start Date
November 2015
End Date
April 2019
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Anne Arundel Health System Research Institute
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Measurable Knee Flexion Contracture, with deficit limiting Active Range of Motion (AROM) and Passive Range of Motion (PROM) by at least - 10°
  • 18 years of age and older
  • Able to understand informed consent and willingness to conform to trial responsibilities

Exclusion Criteria

  • Previous surgical treatment of knee, including tibial osteotomy
  • Botulinum Toxin Treatment within the last four months
  • Mechanical joint impingement
  • Neuromuscular pathologies such as epilepsy
  • Treatment with quinolone, antibiotic medication
  • Pregnant or nursing
  • Osteomyelitis or any orthopedic infection
  • Extensor mechanism dysfunction
  • Knee joint neuropathy
  • Previous Stroke or Brain Injury

Outcomes

Primary Outcomes

AROM

Time Frame: 4 weeks after randomization

Change in maximal active range of motion in

Secondary Outcomes

  • AROM(2 weeks postoperatively)

Study Sites (1)

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