Observational Studies, Prospective, Multicenter, to Evaluate the Effect of Treatment of Knee Osteochondral Lesions of Outerbridge Grade III-IV
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Degenerative Lesion of Articular Cartilage of Knee
- Sponsor
- Ettore Sansavini Health Science Foundation
- Enrollment
- 20
- Locations
- 4
- Primary Endpoint
- International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Score
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The purpose of the study is to evaluate prospectively the outcome of treatment interventions of knee osteochondral lesions Outerbridge grade III and IV.
Detailed Description
The main purpose of the study is to prospectively evaluate the outcome of treatment interventions with replacement, repair and regenerative approaches, of osteochondral articular lesions or defects, Outerbridge grade III and IV, in terms of symptomatic and functional recovery 12 months after surgery.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Score
Time Frame: 12 months post procedure
Primary outcome measure will be the outcome of innovative treatments with repairing, regenerative and replacement techniques, with or without associated osteotomy, of knee osteochondral severe lesions(Outerbridge grade III and IV) in terms of symptoms improvement as assessed by means of the International Knee Documentation Committee (IKDC) subjective Knee Evaluation Score at 12 months postoperatively.
Secondary Outcomes
- functional recovery at International Knee Documentation Committee(IKDC) knee Examination(12 months)
- Tissue regeneration at magnetic resonance (MRI)(12 months post surgery)
- Physical performance at Tegner activity score(12 months post surgery)
- functional activity on the Lysholm Knee Scale(12 months post surgery)