Comparison the effect of Dexmedetomidine and Magnesium Sulphate on hemodynamic changes during laparoscopic cholecystectomy surgery
Phase 2
- Conditions
- Cholecystectomy.Acquired absence of other parts of digestive tract
- Registration Number
- IRCT2017092136312N1
- Lead Sponsor
- Vice chancellor for research, Golestan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Participants including major eligibility criteria: age between 18 to 55 years old; American Society of Anesthesiologists (ASA) physical status classification system I and II; under general anesthesia and tracheal intubation; filling the written informed consent form.
Exclusion Criteria
with cardiovascular, hepatic, and renal diseases; substance abuse; Body Mass Index (BMI) greater than 30; Mallampati classification class III and IV.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic and diastolic blood pressure. Timepoint: Before, during, and after surgery. Method of measurement: By sphygmomanometer and in millimeter mercury.;Heart rate. Timepoint: Before, during, and after surgery. Method of measurement: withnon-invasive hemodynamic monitoring device and in beat per minute.;Mean Arterial Pressure (MAP). Timepoint: Before, during, and after surgery. Method of measurement: derived from Systolic Blood Pressure and Diastolic Blood Pressure and in millimeter mercury.
- Secondary Outcome Measures
Name Time Method Shivering. Timepoint: after surgery. Method of measurement: observation of patient.