Effect of dexmedetomidine and magnesium sulphate on propofol consumption, haemodynamics (blood pressure and heart rate) and postoperative recovery in spine surgery

Phase 4

Completed

• Conditions: Health Condition 1: null- ASA grade I or II patient, Non diabetic, Non hypertensive and require General anesthesia with intubation

• Registration Number: CTRI/2013/08/003939
• Lead Sponsor: Apollo Hospitals Bilaspur

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 90

Inclusion Criteria

1.ASA grade I and II,

2.Non hypertensive and non diabetic

3.Scheduled for spinal surgery under general anesthesia

Exclusion Criteria

1.Known allergy to magnesium sulphate or other study drug,

2.Morbid obesity (body mass index >40),

3.Chronic use of opioids and anticoagulants

4.Current treatment with a β-blocker or calcium channel blocker

5.Diabetes and hypertension

6.Known asthma or reactive airway disease,

7.Hepatic, renal or cardiovascular dysfunction

8.Any degree of heart block

9.Haematological disorder

10.History of neuromuscular disease,

11.Patients receiving magnesium supplementation,

12.Drugs known to have a significant interaction with NMDAs

13.Psychiatric patients

14.Pregnant and lactating women

Study & Design

• Study Type: Interventional
• Study Design: Not specified