Effects of Music Beat on Motor Function in Individuals At Risk for Psychotic Onset and Schizophrenia Patients

Not Applicable

Completed

• Conditions: Psychosis; Parkinsonism; Dyskinesias; Schizophrenia
• Interventions: Behavioral: no RAS; Behavioral: Rhythmic auditory stimulation (RAS)

• Registration Number: NCT04929795
• Lead Sponsor: Dr WANG Shumei

Brief Summary

The purpose of this project is to investigate whether a 3-week training program involving music beat (serving as a type of rhythmic auditory stimulation) reduces the severity of bradykinesia and dyskinesia in at-risk individuals and schizophrenia patients. It is hypothesized that the program is effective in reducing the severity of bradykinesia and dyskinesia in at-risk individuals and schizophrenia patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-06-10
• Study First Submitted QC: 2021-06-10
• Study First Posted: 2021-06-18
• Study Start: 2021-08-11
• Primary Completion: 2023-12-31
• Study Completion: 2023-12-31
• Status Verified: 2024-11
• Last Update Submitted: 2024-11-19
• Last Update Posted: 2024-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
schizophrenia- no RAS	no RAS	Schizophrenia patients in the control group will receive upper-limb training without the aid of RAS.
at risk- RAS	Rhythmic auditory stimulation (RAS)	At-risk individuals in the experimental group will undergo upper-limb movement training with the aid of music beat serving as a type of rhythmic auditory stimulation (RAS).
at risk- no RAS	no RAS	At-risk individuals in the control group will receive upper-limb training without the aid of RAS.
schizophrenia- RAS	Rhythmic auditory stimulation (RAS)	Schizophrenia patients in the experimental group will undergo upper-limb movement training with the aid of RAS.

Primary Outcome Measures

Name	Time	Method
Motion analysis by using an eight-camera motion capture system (VICON; Oxford Metrics Group, Oxford, UK)	Within one week right after the last session of the intervention	normalized number of movement units (representing severity of dyskinesia). Unit: units/mm

Trial Locations

Locations (1)

ST814, the Hong Kong Polytechnic University; 🇭🇰 Kowloon, Hong Kong