Comparison of action & side effects of three different doses of drugs that numb pain sensation in the technique used to block the nerves supplying the upper limb
Phase 3
- Conditions
- Health Condition 1: M958- Other specified acquired deformities of musculoskeletal system
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Elective right sided upper limb bony surgeries of humerus, elbow and forearm under brachial plexus block
2. American Society of Anaesthesiologist physical status 1-3
Exclusion Criteria
1.Patients with fractures of the clavicle,
2. BMI > 30,
3.Patients with rib fractures,
4. Pre-existing respiratory disorders,
5. Patients with coagulopathy and pre-existing nerve deficits of the brachial plexus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of phrenic nerve palsy: Reduction in the hemi diaphragmatic excursion by at least 75 % from the baseline value during deep breathing <br/ ><br>Timepoint: 30 minutes post block <br/ ><br>
- Secondary Outcome Measures
Name Time Method Duration of analgesia: Time interval between needle removal & patient reported painTimepoint: The time patient reports pain is taken as the time point for assessment of duration of analgesia;Duration of the motor block: Time to recover to 5 kg of hand grip strength assessed using dynamometerTimepoint: Every hour for the first 12 hours & every 4 hours for the next 12 hours;Time to complete conduction blockade of terminal branches of brachial plexus: Time to reach a total composite score of 20/20 of complete sensory & motor blockade assessed at specific dermatome & muscle function of five terminal branches of the brachial plexusTimepoint: 10,20 & 30 minutes post block