NCT00925223
Unknown
Not Applicable
Study of Brain-derived Neurotrophic Factor in Visceral Hyperalgesia in IBS Patients
Shandong University0 sites30 target enrollmentJune 2009
ConditionsIrritable Bowel Syndrome
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Irritable Bowel Syndrome
- Sponsor
- Shandong University
- Enrollment
- 30
- Last Updated
- 16 years ago
Overview
Brief Summary
Brain-derived neurotrophic factor (BDNF), originally known to be a member of the nerve growth factor family, has aroused attention as a modulator in visceral hyperalgesia recently. Visceral hypersensitivity is recognized as a clinical hallmark in IBS patients. So in this study, the investigators will focus on the role of BDNF in colonic hyperalgesia in IBS patients.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients diagnosed with irritable bowel syndrome.
Exclusion Criteria
- •Patients have similar clinical symptoms as IBS, yet there is morphologic changes in the intestine.
Outcomes
Primary Outcomes
Not specified
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