Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease
- Conditions
- Atherosclerotic Cardiovascular Disease
- Interventions
- Drug: Inclisiran sodium 300 mgDrug: Placebo
- Registration Number
- NCT05030428
- Lead Sponsor
- Novartis Pharmaceuticals
- Brief Summary
Study CKJX839B12302 is a pivotal Phase III trial to evaluate the benefits of inclisiran on major adverse cardiovascular (MACE) events in participants with established cardiovascular disease (CVD).
- Detailed Description
Purpose of this study is to test the hypothesis that treatment with inclisiran sodium 300 mg s.c. administered on Day 1, Month 3 (Day 90), and every 6 months thereafter taken in addition to well-tolerated high-intensity statin therapy in participants with established ASCVD will significantly reduce the risk of 3-Point-Major Adverse Cardiovascular Events (3P-MACE) defined as a composite of CV death, non-fatal myocardial infarction (MI) and non-fatal ischemic stroke. This will be compared to placebo in adjunct to well-tolerated high-intensity statin therapy.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 17004
-
Fasting LDL-C ≥ 70 mg/dL at randomization visit
-
Stable (greater than or equal to 4 weeks) and well-tolerated lipid-lowering regimen (including e.g. with or without Ezetimibe) that must include a high-intensity statin therapy with either atorvastatin greater than or equal to 40 mg QD or rosuvastatin greater than or equal to 20 mg QD
-
Established CV disease defined as ANY of the following three conditions
- Spontaneous Myocardial infarction ≥ 4 weeks from screening visit
- History of ischemic stroke occurred ≥ 4 weeks prior to the Screening visit
- Symptomatic peripheral arterial disease (PAD) evidenced by either intermittent claudication with ankle brachial index (ABI) < 0.85, prior peripheral arterial revascularization procedure, or, amputation due to atherosclerotic disease.
- Acute coronary syndrome, stroke, peripheral arterial revascularization procedure or amputation due to atherosclerotic disease < 4 weeks before screening visit
- Treatment with PCSK9 inhibitors (e.g. evolocumab, alirocumab) within 90 days or planned use post first study visit
- Planned or expected cardiac, cerebrovascular or peripheral artery surgery or re-vascularization within the 6 months after the first study visit
- Heart failure NYHA class III or IV
- Active liver disease defined as any known current infectious, neoplastic, or metabolic pathology of the liver
- Previous exposure to inclisiran or any other non-mAb PCSK9-targeted therapy, either as an investigational or marketed drug within 2 years
- Severe concomitant non-CV disease that is expected to reduce life expectancy to less than 5 years
- History of malignancy that required surgery radiation therapy and/or systemic therapy during the 3 years prior to the first study visit
- Pregnant or nursing (lactating) women
Other protocol-defined inclusion/exclusion criteria may apply.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Inclisiran sodium Inclisiran sodium 300 mg Subcutaneous injection Placebo Placebo Subcutaneous injection
- Primary Outcome Measures
Name Time Method Time to First Occurrence of 3P-MACE (3-Point Major Adverse Cardiovascular Events) From randomization to total follow-up time (up to 72 months) 3P-MACE is a confirmed composite endpoint which includes cardiovascular death, non-fatal myocardial infarction and non-fatal ischemic stroke.
- Secondary Outcome Measures
Name Time Method Time to Occurrence of Cardiovascular (CV) Death From randomization to total follow-up time (up to 72 months) CV death is defined as death due to cardiovascular events
Time to First Occurrence of 4P-MACE (4-Point Major Adverse Cardiovascular Events) From randomization to total follow-up time (up to 72 months) A composite 4P- MACE is defined as CV death, non-fatal MI, non-fatal ischemic stroke and urgent coronary revascularization.
Time to first occurrence of Major Limb Adverse Events (MALE) From randomization to total follow-up time (up to 72 months) Major Limb Adverse Events including acute lower limb ischemia, lower limb amputation due to ischemia, or urgent lower limb revascularization for ischemia
Time to occurrence of all-cause death From randomization to total follow-up time (up to 72 months) All-Cause death is defined as: all deaths from randomization until up to 72 months
Trial Locations
- Locations (267)
CCT Research
🇺🇸Omaha, Nebraska, United States
Pima Heart And Vascular Clin Rch
🇺🇸Tucson, Arizona, United States
ARcare Center for Clinical Research
🇺🇸Little Rock, Arkansas, United States
Arkansas Clinical Research
🇺🇸Little Rock, Arkansas, United States
Central Cardiology Medical Center
🇺🇸Bakersfield, California, United States
John Muir Physician Network Clinical Research Center
🇺🇸Concord, California, United States
ASCADA Research
🇺🇸Fullerton, California, United States
Diabetes Lipid Management Center
🇺🇸Huntington Beach, California, United States
University of Calif Irvine Med Cntr
🇺🇸Irvine, California, United States
A&A Research Group Inc
🇺🇸Miami, Florida, United States
Eminat LLC
🇺🇸Miramar, Florida, United States
Ocala Cardiovascular Research
🇺🇸Ocala, Florida, United States
Oviedo Medical Research
🇺🇸Oviedo, Florida, United States
CTMD Research
🇺🇸Palm Springs, Florida, United States
Broward Research Center
🇺🇸Pembroke Pines, Florida, United States
SEC Clinical Research
🇺🇸Pensacola, Florida, United States
Southern Clinical Research
🇺🇸Zachary, Louisiana, United States
Sinai Ct for Throm Res and Drug Dev
🇺🇸Baltimore, Maryland, United States
Metropolitan Cardiovascular Consultants Llc
🇺🇸Beltsville, Maryland, United States
The Valley Hospital
🇺🇸Ridgewood, New Jersey, United States
Bassett Medical Center
🇺🇸Cooperstown, New York, United States
NYU Langone Hlth Card Assoc
🇺🇸Mineola, New York, United States
Ascension St Vincents
🇺🇸Birmingham, Alabama, United States
Elite Clinical Studies
🇺🇸Phoenix, Arizona, United States
HonorHealth Heart Group Deer Valley
🇺🇸Scottsdale, Arizona, United States
Hope Clinical Research
🇺🇸Canoga Park, California, United States
UC San Diego Health
🇺🇸La Jolla, California, United States
Keck Medical Center USC
🇺🇸Los Angeles, California, United States
VA Palo Alto Health Care System
🇺🇸Palo Alto, California, United States
West Coast Research LLC
🇺🇸San Ramon, California, United States
Encompass Clinical Research
🇺🇸Spring Valley, California, United States
Stanford University Medical Center
🇺🇸Stanford, California, United States
Blue Coast Research Center LLC
🇺🇸Vista, California, United States
d-b-a Greenwich Cardio Assoc
🇺🇸Greenwich, Connecticut, United States
Emerson Clinical Research Institute
🇺🇸Washington, District of Columbia, United States
Nova Clinical Research LLC
🇺🇸Bradenton, Florida, United States
Westside Center for Clinical Research
🇺🇸Jacksonville, Florida, United States
University of Florida Health Science Center
🇺🇸Jacksonville, Florida, United States
Advanced Research for Health Improvement LLC
🇺🇸Naples, Florida, United States
Advanced Medical Research Center
🇵🇷San Juan, Puerto Rico
James A Haley Veterans Hospital
🇺🇸Tampa, Florida, United States
Genesis Clinical Research
🇺🇸Tampa, Florida, United States
BayCare Health System
🇺🇸Tampa, Florida, United States
Northeast Georgia Medical Center
🇺🇸Gainesville, Georgia, United States
Atlanta Heart Specialists LLC
🇺🇸Tucker, Georgia, United States
Biofortis Research
🇺🇸Addison, Illinois, United States
Northwest Heart Clinical Rsrch LLC
🇺🇸Arlington Heights, Illinois, United States
Gateway Cardiology PC
🇺🇸Jerseyville, Illinois, United States
Franciscan Health Services Research Center
🇺🇸Indianapolis, Indiana, United States
Witham Health Services
🇺🇸Lebanon, Indiana, United States
Covenant Medical Center
🇺🇸Waterloo, Iowa, United States
University of Kansas Hospital
🇺🇸Kansas City, Kansas, United States
Ascension Via Christi Research
🇺🇸Wichita, Kansas, United States
University of Kentucky College of Health Sciences
🇺🇸Lexington, Kentucky, United States
U of Louisville Rudd Heart and Lung
🇺🇸Louisville, Kentucky, United States
Cambridge Medical Trials
🇺🇸Alexandria, Louisiana, United States
Louisiana Cardiology Associates
🇺🇸Baton Rouge, Louisiana, United States
Grace Research LLC
🇺🇸Bossier City, Louisiana, United States
Cardiovascular Associates Research
🇺🇸Covington, Louisiana, United States
Louisiana Heart Center Research
🇺🇸Slidell, Louisiana, United States
Clinical Trials Management LLC
🇺🇸Mandeville, Louisiana, United States
Barnum Medical Research Inc
🇺🇸Natchitoches, Louisiana, United States
Crescent City Physicians Inc
🇺🇸New Orleans, Louisiana, United States
Grace Research Llc
🇺🇸Shreveport, Louisiana, United States
Anderson Medical Research
🇺🇸Fort Washington, Maryland, United States
Javara Inc
🇺🇸Glenn Dale, Maryland, United States
Tidal Health Peninsula Regional Inc
🇺🇸Salisbury, Maryland, United States
Tufts Medical Center
🇺🇸Boston, Massachusetts, United States
Dana Farber Cancer Institute
🇺🇸Boston, Massachusetts, United States
VA Boston Healthcare System
🇺🇸Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center
🇺🇸Boston, Massachusetts, United States
Henry Ford Hospital
🇺🇸Detroit, Michigan, United States
MyMichigan Medical Center Midland
🇺🇸Midland, Michigan, United States
Traverse Heart and Vascular
🇺🇸Traverse City, Michigan, United States
Trinity Health Michigan Heart
🇺🇸Ypsilanti, Michigan, United States
University Of Minnesota
🇺🇸Minneapolis, Minnesota, United States
Regions Hospital
🇺🇸Saint Paul, Minnesota, United States
Cardiology Associates of North MS
🇺🇸Tupelo, Mississippi, United States
St Louis V A Medical Center
🇺🇸Saint Louis, Missouri, United States
Mercy South
🇺🇸Saint Louis, Missouri, United States
St Louis Heart and Vascular
🇺🇸Saint Louis, Missouri, United States
Mercy Hospital
🇺🇸Springfield, Missouri, United States
Physician Research Collaboration
🇺🇸Lincoln, Nebraska, United States
VA Medical Center - NWI, Endocrine Studies (R151)
🇺🇸Omaha, Nebraska, United States
Clinical Research of South Nevada
🇺🇸Las Vegas, Nevada, United States
Cooper University Health Care
🇺🇸Haddon Heights, New Jersey, United States
Robert Wood Johnson Medical School
🇺🇸New Brunswick, New Jersey, United States
Cardio Metabolic Institute
🇺🇸Somerset, New Jersey, United States
New Mexico Heart Institute
🇺🇸Albuquerque, New Mexico, United States
Albany Medical College
🇺🇸Albany, New York, United States
Meridian Clinical Research
🇺🇸Binghamton, New York, United States
Meridian Clinical Research LLC
🇺🇸Endwell, New York, United States
Westchester Medical Center
🇺🇸Valhalla, New York, United States
Novant Health Heart and Vascular Institute
🇺🇸Charlotte, North Carolina, United States
Lucas Research
🇺🇸Morehead City, North Carolina, United States
Wake Forest University Baptist Medical Center
🇺🇸Winston-Salem, North Carolina, United States
Akron Hospital Summa Health System
🇺🇸Akron, Ohio, United States
University Of Cincinnati
🇺🇸Cincinnati, Ohio, United States
University Hospitals Cleveland Medical Center
🇺🇸Cleveland, Ohio, United States
Oklahoma Heart Institute
🇺🇸Tulsa, Oklahoma, United States
UPMC
🇺🇸Pittsburgh, Pennsylvania, United States
Kent County Memorial Hospital
🇺🇸Warwick, Rhode Island, United States
Medical Univ Of South Carolina
🇺🇸Charleston, South Carolina, United States
Prisma Health Upstate
🇺🇸Greenville, South Carolina, United States
Family Medicine of Sayebrook
🇺🇸Myrtle Beach, South Carolina, United States
Sanford University of South Dakota Medical Center
🇺🇸Sioux Falls, South Dakota, United States
North Central Heart
🇺🇸Sioux Falls, South Dakota, United States
The Jackson Clinic PA
🇺🇸Jackson, Tennessee, United States
Turkey Creek Medical Center
🇺🇸Knoxville, Tennessee, United States
Cardiovascular Res of Knoxville LLC
🇺🇸Powell, Tennessee, United States
PharmaTex Research LLC
🇺🇸Amarillo, Texas, United States
North Hills Medical Research Inc
🇺🇸Bedford, Texas, United States
VA North Texas Health Care System
🇺🇸Dallas, Texas, United States
North Texas Endocrine Center
🇺🇸Dallas, Texas, United States
Research Institute of Dallas PA
🇺🇸Dallas, Texas, United States
Houston Methodist Hospital
🇺🇸Houston, Texas, United States
FMC Science
🇺🇸Lampasas, Texas, United States
CardioVoyage LLC
🇺🇸McKinney, Texas, United States
Discovery Clinical Trials
🇺🇸Pflugerville, Texas, United States
Heartplace-Plano
🇺🇸Plano, Texas, United States
University of Texas Health Science Center At San Antonio
🇺🇸San Antonio, Texas, United States
South Texas Cardiovascular Consultants PLLC
🇺🇸San Antonio, Texas, United States
Endeavor Clinical Trials
🇺🇸San Antonio, Texas, United States
Sherman Clinical Research
🇺🇸Sherman, Texas, United States
Progressive Clinical Research
🇺🇸Bountiful, Utah, United States
Burke Internal Medicine and Research
🇺🇸Burke, Virginia, United States
York Clinical Research
🇺🇸Norfolk, Virginia, United States
University of Washington
🇺🇸Seattle, Washington, United States
Universal Research Group LLC
🇺🇸Tacoma, Washington, United States
Advanced Clinical Research LLC
🇵🇷Bayamon, Puerto Rico
Eastern Shore Research Institute
🇺🇸Fairhope, Alabama, United States
G and L Research LLC
🇺🇸Foley, Alabama, United States
Alaska Heart and Vascular
🇺🇸Anchorage, Alaska, United States
Mercy Gilbert Medical Center
🇺🇸Gilbert, Arizona, United States
Cardiovascular Associates of Mesa
🇺🇸Mesa, Arizona, United States
Clinical Research Inst of Arizona
🇺🇸Sun City West, Arizona, United States
American Institute of Research
🇺🇸Los Angeles, California, United States
University of California LA
🇺🇸Los Angeles, California, United States
San Diego Veterans Medical Center
🇺🇸San Diego, California, United States
Helping Hands Medical Associates INC
🇺🇸Santa Ana, California, United States
Syrentis Clinical Research
🇺🇸Santa Ana, California, United States
Manshadi Heart Institute
🇺🇸Stockton, California, United States
Uni of California at Los Angeles
🇺🇸Torrance, California, United States
Tilda Research
🇺🇸Tustin, California, United States
Interv Cardiology Med Grp
🇺🇸West Hills, California, United States
Aurora Denver Cardiology Associates
🇺🇸Aurora, Colorado, United States
Rocky Mountain Regional VA Med Ctr
🇺🇸Aurora, Colorado, United States
Bridgeport Hospital
🇺🇸Bridgeport, Connecticut, United States
Chase Medical Research LLC
🇺🇸Waterbury, Connecticut, United States
Excel Medical Clinical Trials LLC
🇺🇸Boca Raton, Florida, United States
Cardiovascular and Vein Center of Florida
🇺🇸Bradenton, Florida, United States
Bay Care Medical Group
🇺🇸Clearwater, Florida, United States
Cardiology Research Associates
🇺🇸Daytona Beach, Florida, United States
Hillcrest Medical Research
🇺🇸DeLand, Florida, United States
Indago Research and Health Ctr Inc
🇺🇸Hialeah, Florida, United States
National Research Institute
🇺🇸Hialeah, Florida, United States
Sister Life Research Inc
🇺🇸Hialeah, Florida, United States
Zenith Clinical Research
🇺🇸Hollywood, Florida, United States
Baptist Heart Specialists
🇺🇸Jacksonville Beach, Florida, United States
United Vein and Vascular Centers
🇺🇸Lake Worth, Florida, United States
Inpatient Research Clinical LLC
🇺🇸Miami Lakes, Florida, United States
RM Medical Research Inc
🇺🇸Miami Lakes, Florida, United States
Infinite Clinical Research
🇺🇸Miami, Florida, United States
Peace River Cardiovascular Center
🇺🇸Port Charlotte, Florida, United States
New Tampa Health
🇺🇸Tampa, Florida, United States
BayCare Medical Group Inc
🇺🇸Tampa, Florida, United States
Ravessa Clinical Research
🇺🇸Tampa, Florida, United States
Cardiology Partners Clinical Research Institute
🇺🇸Wellington, Florida, United States
Javara Research
🇺🇸Forest, Virginia, United States
Alta Pharmaceutical Research Center
🇺🇸Peachtree Corners, Georgia, United States
Solaris Clinical Research
🇺🇸Meridian, Idaho, United States
Saltzer Health
🇺🇸Nampa, Idaho, United States
Cedar Crosse Research Ct
🇺🇸Chicago, Illinois, United States
Chicago Clinical Research Inst
🇺🇸Chicago, Illinois, United States
Methodist Med Center Of Illinois
🇺🇸Peoria, Illinois, United States
SIU School of Medicine
🇺🇸Springfield, Illinois, United States
Prairie Heart Institute
🇺🇸Springfield, Illinois, United States
Elkhart Cardiology Group
🇺🇸Elkhart, Indiana, United States
The Heart Center of Lake County
🇺🇸Merrillville, Indiana, United States
Cardiovascular Research Of Northwest Indiana, Llc
🇺🇸Munster, Indiana, United States
Midwest Heart and Vascular Spec
🇺🇸Overland Park, Kansas, United States
Cotton O Neil Clinical Res Center
🇺🇸Topeka, Kansas, United States
Avant Research Associates LLC
🇺🇸Crowley, Louisiana, United States
Horizon Research Group of Opelousas, LLC
🇺🇸Eunice, Louisiana, United States
Cardiovascular Institute South ASC
🇺🇸Gray, Louisiana, United States
Heart Clinic of Hammond
🇺🇸Hammond, Louisiana, United States
CV Ins of the South
🇺🇸Opelousas, Louisiana, United States
North Shore Heart and Vascular
🇺🇸Mandeville, Louisiana, United States
Omega Clinical Research
🇺🇸Metairie, Louisiana, United States
Clinical Trials of America LA LLC
🇺🇸Monroe, Louisiana, United States
Johns Hopkins University
🇺🇸Columbia, Maryland, United States
Capitol Cardiology Associates
🇺🇸Lanham, Maryland, United States
MD Medical Research
🇺🇸Oxon Hill, Maryland, United States
Adventist HealthCare Shady Grove Medical Center
🇺🇸Rockville, Maryland, United States
ActivMed Practices and Research
🇺🇸Methuen, Massachusetts, United States
AA Medical Research Center
🇺🇸Flint, Michigan, United States
Healthy Heart Cardiology
🇺🇸Grand Rapids, Michigan, United States
McLaren Greater Lansing
🇺🇸Lansing, Michigan, United States
Ascension St Mary s Hospital
🇺🇸Saginaw, Michigan, United States
Providence Hospital Patient Care Research
🇺🇸Southfield, Michigan, United States
St Marys Medical Center
🇺🇸Duluth, Minnesota, United States
North Memorial Heart and Vascular Institute
🇺🇸Robbinsdale, Minnesota, United States
CentraCare Heart and Vascular Center
🇺🇸Saint Cloud, Minnesota, United States
Belzoni Clinical Research
🇺🇸Belzoni, Mississippi, United States
Jackson Heart Clinic
🇺🇸Jackson, Mississippi, United States
VAMC Research-G V Sonny Montgomery Clinic
🇺🇸Jackson, Mississippi, United States
Yazoo Clinical Research .
🇺🇸Yazoo City, Mississippi, United States
Kansas City VA Medical Center
🇺🇸Kansas City, Missouri, United States
North Kansas City Hospital
🇺🇸North Kansas City, Missouri, United States
Gateway Cardiovascular Rsch Ctr Inc
🇺🇸Saint Louis, Missouri, United States
Las Vegas Endocrinology
🇺🇸Henderson, Nevada, United States
AB Clinical Trials
🇺🇸Las Vegas, Nevada, United States
Catholic Medical Center
🇺🇸Manchester, New Hampshire, United States
New Jersey Heart
🇺🇸Linden, New Jersey, United States
Garden State Heart Care
🇺🇸Manalapan, New Jersey, United States
Newark Beth Israel Medical Center
🇺🇸Newark, New Jersey, United States
Weill Cornell Medical Center
🇺🇸New York, New York, United States
Icahn School of Med at Mt Sinai
🇺🇸New York, New York, United States
Northport VA Medical Center
🇺🇸Northport, New York, United States
Rochester Clinical Research
🇺🇸Rochester, New York, United States
State Uni of NY at Stony Brook
🇺🇸Stony Brook, New York, United States
Tryon Medical Partners PLLC
🇺🇸Charlotte, North Carolina, United States
NC Heart and Vascular Research LLC
🇺🇸Raleigh, North Carolina, United States
Accellacare
🇺🇸Knoxville, Tennessee, United States
Altru Health Research Dept.
🇺🇸Grand Forks, North Dakota, United States
Velocity Clin Research Springdale
🇺🇸Cincinnati, Ohio, United States
Kettering Medical Center
🇺🇸Kettering, Ohio, United States
Rama Research LLC
🇺🇸Marion, Ohio, United States
Heart House Research Foundation
🇺🇸Springfield, Ohio, United States
Mercy Health St Vincent Med Ctr
🇺🇸Toledo, Ohio, United States
Premier Cardiovascular Institute
🇺🇸Vandalia, Ohio, United States
Bend Memorial Clinic
🇺🇸Bend, Oregon, United States
Samaritan Cardiology
🇺🇸Corvallis, Oregon, United States
Abington Memorial Hospital
🇺🇸Abington, Pennsylvania, United States
Butler Memorial Hospital
🇺🇸Butler, Pennsylvania, United States
Preferred Primary Care Physicians
🇺🇸Pittsburgh, Pennsylvania, United States
Frontier Clinical Research LLC
🇺🇸Smithfield, Pennsylvania, United States
Columbia Heart Clinic
🇺🇸Columbia, South Carolina, United States
Columbia VA Health Care System
🇺🇸Columbia, South Carolina, United States
Bon Secours Medical Group
🇺🇸Greenville, South Carolina, United States
Trident Cardiology
🇺🇸Ladson, South Carolina, United States
Wellmont CVA Heart Institute
🇺🇸Greenville, Tennessee, United States
Apex Cardiology Research Associates of Jackson
🇺🇸Jackson, Tennessee, United States
Memphis Cardiology and Vein Ct
🇺🇸Memphis, Tennessee, United States
Tennessee Center For Clinical Trials
🇺🇸Tullahoma, Tennessee, United States
Soltero Cardiovascular Research Center
🇺🇸Dallas, Texas, United States
Texas Health Physicians Group
🇺🇸Fort Worth, Texas, United States
SW Family Medicine Associates
🇺🇸Dallas, Texas, United States
David Turbay MD PLLC
🇺🇸El Paso, Texas, United States
UT Physicians Memorial Hermann
🇺🇸Houston, Texas, United States
Orion Medical
🇺🇸Houston, Texas, United States
Village Medical Village MD S Tx
🇺🇸Houston, Texas, United States
East Texas Research Associates Inc.
🇺🇸Livingston, Texas, United States
Privia Medical Group Gulf Coast
🇺🇸Sugar Land, Texas, United States
Alina clinical trials .
🇺🇸Texas City, Texas, United States
Alina clinical trials Baxter REsearch LLC
🇺🇸Texas City, Texas, United States
Heart Care Associates P C
🇺🇸Hopewell, Virginia, United States
Dominion Medical Associates
🇺🇸Richmond, Virginia, United States
Roanoke Heart Institute
🇺🇸Roanoke, Virginia, United States
Winchester Medical Center
🇺🇸Winchester, Virginia, United States
Virginia Mason Medical Centre
🇺🇸Seattle, Washington, United States
Swedish Medical Center-Cardiovascular Research
🇺🇸Seattle, Washington, United States
Confluence Health Hospital
🇺🇸Wenatchee, Washington, United States
Novartis Investigative Site
🇹🇷Konya, Turkey
Research and Cardiovascular Corp
🇵🇷Ponce, Puerto Rico
Latin Clinical Trial Center Inc
🇵🇷San Juan, Puerto Rico
Barbara Diaz Hernandez Research Inc
🇵🇷San Juan, Puerto Rico