ISRCTN69503018已完成未知
Gene expression in patients with polymyalgia rheumatica and control subjects before and after glucocorticoid treatment
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Age 50 years or older
- •2. Bilateral aching and stiffness persisting for 1 month or more involving two of the following areas: neck or torso, shoulders or proximal regions of the arms, and hips or proximal aspects of the thighs
- •3. Erythrocyte sedimentation rate >40 mm/h
- •4. Exclusion of other diagnoses except giant cell arteritis
- •Control participants:
- •Aged 50 years or older
排除标准
- •Patients and control participants:
- •1. Prior treatment with glucocorticoids
- •2. Diagnosis of GCA based on obligatory temporal artery biopsy (patients only)
- •3. Inflammatory conditions other than PMR
- •4. Cancer during the past 5 years
- •5. Neuromuscular disease
- •6. Severe infections
- •7. Hereditary disposition for type 2 diabetes
- •8. Thyroid disease
- •9. Disturbance of calcium homeostasis
- •10. Uncontrolled hypertension
- •11. Use of drugs with potential effects on the study parameters
研究者
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