Predictors of relapse in Polymyalgia Rheumatica patients treated with low-dose glucocorticoid therapy

Austin Health0 个研究点目标入组 35 人开始时间: 2014年7月2日最近更新: 2022年9月12日

适应症

试验速览

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•New diagnosis of Polymyalgia Rheumatica as defined by the 2012 EULAR/ACR Classification Criteria:
•- Age >= 50 years;
•- Bilateral shoulder aching;
•- Abnormal ESR and/or CRP;
•PLUS a score of >=4 based upon a scoring algorithm:
•- Morning stiffness duration >45 mins (2 points);
•- Hip pain or limited range of movement (1 point);
•- Negative rheumatoid factor and/or ACPA (2 points);
•- Absence of peripheral joint pain (1 point).

•- Inability to provide informed consent;
•- Symptoms suggestive of Giant Cell Arteritis (headache, jaw claudication, scalp tenderness or visual disturbance);
•- Cancer within the past 5 years;
•- Neuromuscular disease;
•- Active infection;
•- Other inflammatory conditions eg. RA;
•- Chronic pain syndromes;
•- Uncontrolled psychiatric conditions, hypertension or diabetes;
•- Treatment with glucocorticoids for >7 days prior to screening or a dose >15mg/day.
•- Treatment with concomitant Disease Modifying Anti-Rheumatic Drugs.

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