Laparoscopic Guided Peri-wound Transversus Abdominis Plane Block With Bupivacaine Versus Local Wound Infiltration on Post-op Opioid Use in Laparoscopic Sleeve Gastrectomy

Phase 2

Recruiting

• Conditions: Morbid Obesity; Bupivacine; Local Wound Infiltration; Laparoscopic Sleeve Gastrectomy; Transversus Abdominis Plane Block; Opioid Use
• Interventions: Procedure: Local wound infiltration; Procedure: peri-wound Transversus Abdominis Plane Block

• Registration Number: NCT05930184
• Lead Sponsor: Khon Kaen University

Brief Summary

The goal of this randomized controlled trial is to compare laparoscopic guided peri-wound Transversus Abdominis Plane Block and bupivacaine versus local wound infiltration effect on reducing post-op opioid use in Laparoscopic Sleeve gastrectomy. The main questions it aims to answer are:

• Can laparoscopic guided peri-wound Transversus Abdominis Plane Block reduced post operative morphine usage when comparing with local wound port site infiltration.

Participants will be randomize into 2 group

* peri-wound Transversus Abdominis Plane Block

* local wound port site infiltration

Detailed Description

Not available

Study Timeline

• Study Start: 2023-04-29
• Study First Submitted: 2023-06-24
• Study First Submitted QC: 2023-06-24
• Study First Posted: 2023-07-05
• Primary Completion: 2024-01-29
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-29
• Last Update Posted: 2024-05-01
• Study Completion: 2024-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 98

Inclusion Criteria

• patient undergoing LSG at Sringarind hospital as indicated by Thai guideline

Exclusion Criteria

• Allergic/contraindicated to bupivacaine, morphine, fentanyl, NSAIDs or Nefopam
• Unable to describe pain score Opioid addict
• denied consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
local wound infiltration	Local wound infiltration	0.25% Bupivacaine 20ml was injected into the wound subcutaneous tissue after the laparoscopic port was removed
peri-wound Transversus Abdominis Plane Block	peri-wound Transversus Abdominis Plane Block	0.25% Bupivacaine 20ml was injected into the transversus abdominis plane around the wound before the laparoscopic port was removed

Primary Outcome Measures

Name	Time	Method
Cumulative morphine use	48hours after intervention

Secondary Outcome Measures

Name	Time	Method
opioid side effect	within admission
PACU time	1day after intervention
postop complication	2weeks after intervention
Post op VAS pain score	48hours after intervention
length of hospital stay	within admission

Trial Locations

Locations (1)

Srinagarind hospital; 🇹🇭 Khon Kaen, Northeastern, Thailand