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The Cleveland Clinic Foundation

The Cleveland Clinic Foundation logo
🇺🇸United States
Ownership
Subsidiary, Private
Established
1921-01-01
Employees
1K
Market Cap
-
Website
http://www.clevelandclinic.org

Clinical Trials

801

Active:47
Completed:458

Trial Phases

6 Phases

Early Phase 1:18
Phase 1:30
Phase 2:48
+3 more phases

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (595 trials with phase data)• Click on a phase to view related trials

Not Applicable
411 (69.1%)
Phase 4
62 (10.4%)
Phase 2
48 (8.1%)
Phase 1
30 (5.0%)
Phase 3
26 (4.4%)
Early Phase 1
18 (3.0%)

Imaging Assessments of ARPKD Kidney Disease Progression

Recruiting
Conditions
Autosomal Recessive Polycystic Kidney Disease
First Posted Date
2025-10-01
Last Posted Date
2025-10-01
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
60
Registration Number
NCT07201025
Locations
🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease

Not Applicable
Recruiting
Conditions
Parkinson Disease
Interventions
Drug: CREXONT ER
First Posted Date
2025-08-24
Last Posted Date
2025-08-24
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
22
Registration Number
NCT07138560
Locations
🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality

Not Applicable
Recruiting
Conditions
GLP - 1
Bowel Preparation for Colonoscopy
Interventions
Drug: Continue GLP/GIP
First Posted Date
2025-08-17
Last Posted Date
2025-08-17
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
120
Registration Number
NCT07127354
Locations
🇺🇸

Cleveland Clinic, Cleveland, Florida, United States

🇺🇸

Cleveland Clinic Weston, Weston, Florida, United States

Surveillance Trial of the Apple Watch in Reliable Burden Assessment in Unseen Recurrence of Surgically Treated AF

Recruiting
Conditions
Atrial Fibrillation
First Posted Date
2025-08-14
Last Posted Date
2025-08-14
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
75
Registration Number
NCT07122947
Locations
🇺🇸

Washington University School of Medicine in St. Louis, St. Louis, Missouri, United States

🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease

Not Applicable
Recruiting
Conditions
Parkinson Disease
First Posted Date
2025-08-07
Last Posted Date
2025-10-02
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
10
Registration Number
NCT07110376
Locations
🇺🇸

Cleveland Clinic, Cleveland, Ohio, United States

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News

Metabolic Surgery Demonstrates Superior Long-Term Outcomes Over GLP-1 Receptor Agonists in Diabetes and Obesity

A Cleveland Clinic study of 3,932 patients found that metabolic surgery reduced all-cause mortality by 32% compared to GLP-1 receptor agonist treatment over a median 5.9-year follow-up period.

Kodiak Sciences' KSI-101 Demonstrates 62% Vision Improvement in Phase 1b MESI Trial

Over 60% of patients receiving KSI-101 at top dose levels achieved 3-line or more vision gains in the Phase 1b APEX study for macular edema secondary to inflammation.

ALONE-AF Trial Shows Discontinuing Anticoagulants After Successful AFib Ablation Reduces Bleeding Risk

The ALONE-AF trial demonstrated that discontinuing oral anticoagulant therapy one year after successful atrial fibrillation ablation resulted in significantly lower rates of stroke, systemic embolism, and major bleeding compared to continuing therapy.

Mavacamten Fails to Show Significant Benefit in Non-Obstructive Hypertrophic Cardiomyopathy Trial

The phase III ODYSSEY-HCM trial involving 580 patients showed mavacamten did not significantly improve symptoms or exercise capacity compared to placebo in non-obstructive hypertrophic cardiomyopathy patients at 48 weeks.

Cleveland Clinic Deploys AI Platform to Accelerate Clinical Trial Recruitment Across Multiple Specialties

Cleveland Clinic has launched Dyania Health's Synapsis AI platform across its clinical research enterprise following successful pilot programs in cardiology, oncology, and neurology.

iMDx Enrolls First Patient in GraftAssureDx Transplant Rejection Monitoring Trial

iMDx has enrolled its first patient in the GraftAssureDx clinical trial, an observational study designed to validate a kitted transplant rejection monitoring test for kidney transplant recipients.

NeOnc Technologies Receives FDA Authorization for Phase II Brain Cancer Trial of NEO212

NeOnc Technologies received FDA authorization to proceed with Phase IIa/IIb clinical trial of NEO212, a first-in-class oral chemical conjugated chemotherapy candidate for brain cancer.

Retension Pharmaceuticals Secures $15M Series B to Advance Novel Hypertension Drug RTN-001 into Phase 2b Trial

Retension Pharmaceuticals completed a $15 million Series B financing round to advance RTN-001, a novel PDE5 inhibitor designed for uncontrolled and resistant hypertension treatment.

Biomerica Appoints Scott Madel as Chief Commercial Officer to Drive inFoods IBS Test Commercialization

Biomerica has appointed Scott Madel as Chief Commercial Officer to accelerate commercialization of its inFoods IBS diagnostic test, bringing over 20 years of experience in laboratory testing and clinical diagnostics.

LifePlus Achieves Clinical Validation for Revolutionary Non-Invasive Glucose and Blood Pressure Monitoring Device

LifePlus announced clinical validation of LifeLeaf®, the world's first non-invasive wearable for continuous glucose and blood pressure tracking, tested at Mayo Clinic, Cleveland Clinic, and other global centers.

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