The Study of Vitamin D Supplement-aid in the treatment of Helicobacter Pylori eradicatio

Phase 3

Recruiting

• Conditions: Dyspepsia due to Helicobacterpylori.; Functional dyspepsia

• Registration Number: IRCT20180922041089N2
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 25 February 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Age over 18 years
A test of the fecal antigen of the Helicobacter pylori or Rapid urease test (RUT) is positive
All patients with functional dyspepsia of the pseudo-ulcer type who did not respond to (or recurring) acid reflux therapy, or the presence or history of gastric or duodenal peptic ulcer in a patient or first-degree relatives of patients with gastric cancer
Informed consent Form

Exclusion Criteria

The history of epilepsy
History of chronic diseases (CHB, CKD, COPD, recurrent CVA or dementia, liver cirrhosis)
Patients own cancers
Severe psychiatric illnesses such as schizophrenia, major depression, bipolar disorders
History of antibiotic use in the last 6 weeks
Patients with dyspepsia with a predominant symptom of reflux
Drug, alcohol and cigarettes
History of gastric surgeries, IBD, diabetes, pathological weight loss (weight loss over 10% of body weight over the past 6 months)
Anemia (Hemoglobin in men under 14 in males under 11 and in menopausal women under 12 (1))
Diabetes (if FBS is greater than or equal to 126 or HbA1c greater than or equal to 6.5%)
corticosteroids use in the last 3 months
Use of vitamin D supplements with therapeutic doses during the last 3 months or during the study
Participate in another research project over the past 3 months
Pregnancy or breastfeeding
History of H pylori infection treatment in the past
History of kidney stones
Participants' unwillingness to take medication or placebo
History of any allergy or side effects
BMI greater than 40

Study & Design

• Study Type: interventional
• Study Design: Not specified