Evaluation of Post-extraction Socket Preservation With Camelline Versus Bovine Deproteinized Xenograft (Pilot Trial)
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 10
- 主要终点
- patient-reported outcome
研究概览
简要总结
Alveolar ridge preservation following tooth extraction has the ability to maintain the ridge dimensions and allow the implant placement in an ideal position fulfilling both functional and aesthetic results. Postextraction socket healing commonly results in resorption of the alveolar ridge.
To prevent this clinical situation, different authors have described several surgical procedures, ranging from regenerative techniques for socket preservation to immediate implant placement. Regenerative techniques have been widely tested in controlled and uncontrolled studies with various materials and clinical approaches: bone grafting alone, including autografts, allografts, xenografts, and alloplasts; membrane alone, whether absorbable or not; and membrane in conjunction with grafting.
详细描述
Various classic studies in the 1960s showed that the resorption process of the postextraction alveolus in both jaws was significantly more pronounced on the buccal aspect. This comes as no surprise, as the buccal surface of the anterior alveolar ridge is commonly thin and fragile. The maxilla tends to exhibit greater reductions in width than in height. The loss of tissue contour takes place mostly during the first 1 to 3 months following tooth extraction. Because the healing patterns of human sockets are unpredictable architecture), then such common procedures as extractions may lead to intraoral situations in which the remaining healed ridge does not allow for an esthetic and functional solution without the aid of significant bone grafting.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
single blinded
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Teeth with: root fractures, endodontic treatment failures, advanced caries lesions or any other cause that make tooth non-restorable and indicated for extraction.
- •Healthy non-smoker patients
排除标准
- •Medically compromised patients.
- •Pregnant females.
- •History of malignancy or radiotherapy/chemotherapy for malignancy in the past 5 years.
- •History of active bone metabolic disease.
研究组 & 干预措施
socket preservation with camelline bone
natural hydroxyapatite derived from camels prepared by investigator
干预措施: socket preservation procedure (Procedure)
socket preservation with bovine bone
natural hydroxyapatite derived from cows (Bio-Oss)
干预措施: socket preservation procedure (Procedure)
结局指标
主要结局
patient-reported outcome
时间窗: within first week postoperatively
assessment of post-operative complication( pain, swelling, bleeding, infection)
次要结局
- ridge contour changes(3 month, 6 month)
研究者
Ghada Adayil
Teaching Assisstant
Cairo University