Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A-PRF) Versus Platelet Rich Fibrin (PRF) A Randomized Clinical Trail :Comparative Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Alveolar Bone Resorption
- Sponsor
- Cairo University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Change in bucco-lingual dimensions
- Last Updated
- 5 years ago
Overview
Brief Summary
the aim of this study is clinically and radiographically evaluate the use of advance platelet rich fibrin (A-PRF) versus platelet rich fibrin (PRF) in preservation of alveolar ridge following tooth extraction
Detailed Description
systemically healthy patients who have at least one non-restorable tooth in the upper inter-bicuspid region and are not seeking immediate or early implant treatment will be allocated in this study after performing nonsurgical periodontal therapy and preoperative periapical therapy to evaluate and improve the condition of the periodontal tissues. Anesthesia will be given then flapless atraumatic extraction using periotomes followed by forceps after luxation. For all groups, the socket will be debrided using curette then * group A, the socket will be filled with A.PRF * group B the socket will be filled with PRF. * group C no bio-additive will be added. * Criss cross horizontal mattress suture will be applied to close the extraction wound. PRF and A-PRF preparation : 10 ml of blood will be drawn from each patient by vein puncture of the antecubital vein. * Plateletr ich fibrin (PRF) is 3000 rpm and 10 minutes without addition of anticoagulant * Advanced platelet rich fibrin (A-PRF) is 1300 rpm and 8 minutes.
Investigators
Reem Mahmoud AbdAlhameed AbuBasha
principal investigator
Cairo University
Eligibility Criteria
Inclusion Criteria
- •Patients with at least one non restorable tooth in upper inter-bicuspid region.
- •Stable periodontal condition with no acute periapical infection.
- •Systematically healthy conditions.
- •Cooperative patients.
- •Intact buccal plate of bone.
Exclusion Criteria
- •Patients seeking immediate or early implants.
- •Pregnant females.
- •Bone diseases.
- •Drugs and diseases that may affect platelet count or function.
Outcomes
Primary Outcomes
Change in bucco-lingual dimensions
Time Frame: 6 months
clinical measurement using bone caliper in mm numerical
Secondary Outcomes
- bone dentistry(6 months)
- postoperative pain scores(2 weeks)
- change in alveolar bone height(6 months)
- soft tissue healing(6 months)