Advanced platelet fibrin in alveolar bone formation
- Conditions
- with intra bony defectsFactors influencing health status and contact with health services,
- Registration Number
- CTRI/2020/03/024204
- Lead Sponsor
- M Bhagya shree
- Brief Summary
A randomized clinical rail will be conducted by the Department of Periodontology , NarayanaDental College and Hospital, Nellore, Andhra pradesh, India.
A total of minimum 20 sites with intra-bony defects will be selected. After full mouth scaling and root planning selected participants will be randomized into following groups.
Group A: Open flap debridement (OFD)
Group B: Open flap debridement (OFD) with Advanced platelet rich fibrin (A-PRF)
Plaque index, Modified sulcular bleeding index, Probing pocket depth, Relative attachment gain and radiographic bone fill will be done at baseline and 6 months.
All the parameters willl be subjected for statistical analysis after completion of the study to evaluate the bone fill between the groups in intra-bony defect.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 20
Diagnosed with intra-bony defects More than 20 teeth present Systemically healthy and not under antibiotics since past 6 months Intra bony defect >3mm radiographicaly Probing pocket depth >5mm.
Systemic diseases that influence periodontal disease and therapy Subjects who were on antibiotics in past six months Pregnant and lactating women.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pocket probing depth, Relative clinical attachment level gain, plaque index, Modified sulcular bleeding index 6months
- Secondary Outcome Measures
Name Time Method Bone fill 6months
Trial Locations
- Locations (1)
Narayana dental college
🇮🇳Nellore, ANDHRA PRADESH, India
Narayana dental college🇮🇳Nellore, ANDHRA PRADESH, IndiaVijay Kumar ChavaPrincipal investigator9441978737chava7@hotmail.com