Use of Aspirin in gum diseases
- Conditions
- Chronic Generalised Periodontitis With Mandibular Grade-II Furcation Defects
- Registration Number
- CTRI/2018/04/013337
- Lead Sponsor
- Self
- Brief Summary
A randomized clinical trial will be conducted by the Department of Periodontology, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
A total of 30 patients with mandibular grade-II furcation defects will be selected . After full mouth scaling and root planing selected patients will be assigned to following groups.
Group A: Open Flap Debridement (OFD) with PRF.
Group B: Open Flap Debridement (OFD) with PRF-ASPIRIN COMPLEX.
Gingival index (GI), Plaque Index (PI),Probing Depth (PD),Clinical Attachment Level and Standardized radiographic recordings will be done at baseline and 6 months.
All the parameters will be subjected for statistical analysis after completion of the study to evaluate and compare the bone fill between the groups in grade-II furcation defects .
Significant difference was found in both clinical and radiographic measurements in both groups.Significant radiographic bone fill was observed in PRF-A group
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
- 1.Bilateral mandibular grade II furcation defects according to Glickman’s classification.
- 2.Systemic diseases known to influence the periodontal condition and not receiving any medication known to affect the status.
- 2.Pregnant females.
- 3.Patient who are under antibiotic coverage for past 1 month.
- 4.Patients who had received periodontal therapy with in 6months before study are excluded.
- 5.Patients who are known hypersensitivity or allergy to aspirin are excluded.
- 6.History of alcohol abuse.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparative assessment of grade 2 furcation defect fill with PRF and PRF aspirin complex Baseline and six month postoperative
- Secondary Outcome Measures
Name Time Method Regenerative capacity of PRF alone and PRF aspirin Complex Base line and six month Postoperative
Trial Locations
- Locations (1)
Narayana Dental College Hospital
🇮🇳Nellore, ANDHRA PRADESH, India
Narayana Dental College Hospital🇮🇳Nellore, ANDHRA PRADESH, IndiaPallavarapu PradeepaPrincipal investigator8555976760pradeepabds199@gmail.com