Study comparing intravenous Dexmedetomidine and intravenous Dexmedetomidine for attenuation of hemodynamic responses on laryngoscopy, intubation and skull pin application during open brain surgery
Phase 4
- Conditions
- Health Condition 1: G96- Other disorders of central nervoussystem
- Registration Number
- CTRI/2021/08/035835
- Lead Sponsor
- King George Mrdical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patient belonging to ASA 1and 2
Patient belongings to age 18 to 70 years
Patient giving informed and written consent
Exclusion Criteria
Patient with known allergy or hypersensitivity to dexmedetomidine
Patient with history of ischemic heart disease, second or third degree heart block, head injury, uncontrolled hypertension, uncontrolled diabetes, pregnancy,and previous craniotomy incision
Patient with respiratory disease and predicted difficult airway
Patient who refuse to give consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare mean arterial pressureTimepoint: Baseline 5 min after, 10 min after after drug administration before laryngosopy and intubation, at 1 min, 3 min, 5 min after intubation,before pin insertion at 1min, 5 min, 10 min,20 min,30 min,60 min afterpin insertion,sedation status at baseline and 10 min after drug administration
- Secondary Outcome Measures
Name Time Method To compare systolic and diastolic blood pressure along with sedation score and adverse effectsTimepoint: Baseline 5 min after, 10 min after after drug administration before laryngosopy and intubation, at 1 min, 3 min, 5 min after intubation,before pin insertion at 1min, 5 min, 10 min,20 min,30 min,60 min afterpin insertion,sedation status at baseline and 10 min after drug administration