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Clinical Trials/NCT02827721
NCT02827721
Unknown
Not Applicable

Evaluation of Novel Lung Function Parameters in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Universitätsmedizin Mannheim1 site in 1 country150 target enrollmentJuly 2015
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ConditionsCOPDObstructive Ventilation DisorderPulmonary Emphysema

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
COPD
Sponsor
Universitätsmedizin Mannheim
Enrollment
150
Locations
1
Primary Endpoint
lung clearance index (LCI) as determined by multiple breath washout
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the detection and therapeutic monitoring of COPD.

Registry
clinicaltrials.gov
Start Date
July 2015
End Date
November 2020
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr. Frederik Trinkmann

Principal Investigator

Universitätsmedizin Mannheim

Eligibility Criteria

Inclusion Criteria

  • •known or suspected COPD
  • •known or suspected obstructive ventilation disorder
  • •pulmonary healthy controls

Exclusion Criteria

  • •pregnancy
  • •inability to participate

Outcomes

Primary Outcomes

lung clearance index (LCI) as determined by multiple breath washout

Time Frame: 30 minutes

airway resistance and reactance (R5, X5, R-D5-20) as determined by impulse oscillometry

Time Frame: 30 minutes

Secondary Outcomes

  • repeatability of lung clearance index (LCI)(30 minutes)

Study Sites (1)

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