NCT02827721Unknown不适用
Evaluation of Novel Lung Function Parameters in Patients With Chronic Obstructive Pulmonary Disease (COPD)
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- lung clearance index (LCI) as determined by multiple breath washout
研究概览
简要总结
Current guideline-based criteria defining COPD do not meet the challenges set by the complex pathophysiology of the disease. The investigators therefore aimed to evaluate novel or not widely used diagnostic approaches for the detection and therapeutic monitoring of COPD.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •known or suspected COPD
- •known or suspected obstructive ventilation disorder
- •pulmonary healthy controls
排除标准
- •pregnancy
- •inability to participate
结局指标
主要结局
lung clearance index (LCI) as determined by multiple breath washout
时间窗: 30 minutes
airway resistance and reactance (R5, X5, R-D5-20) as determined by impulse oscillometry
时间窗: 30 minutes
次要结局
- repeatability of lung clearance index (LCI)(30 minutes)
研究者
Dr. Frederik Trinkmann
Principal Investigator
Universitätsmedizin Mannheim
研究点 (1)
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