a comparative study of intraperitoneal instillation of local anesthetic with different drugs after laparoscopic gall bladder removal pain

Phase 3

Not yet recruiting

• Conditions: Calculus of gallbladder without cholecystitis,

• Registration Number: CTRI/2022/06/043378
• Lead Sponsor: Dr meenakshi

Brief Summary

Laparoscopic cholecystectomy is currently the most accepted surgical technique for cholelithiasis

Pain resulting from stretching of intraabdominal cavity peritoneal inflammation and diaphragmatic irritation caused by residual co2 can prolong hospital stay

Many methods are there like local site infiltration  transverse abdominal plane block  post procedure saline lavage but these methods are not recommended unless basic analgesia is possible

Intraperitoneal instillation of local anesthetic with different adjuvants can possibly overcome this postoperative pain

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-06-20
• Study Start: 2022-06-21

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

ASA grade 1 and 2 Patient giving consent Patient having gall bladder stone.

Exclusion Criteria

Patients not giving consent Patient allergic to local anesthetic and study drugs Duration of surgery more than 90 minutes BMI more than 30 kg/m2 Patients with acute cholecystitis Patients with cardiac pulmonary and neurological disease Patients with deranged LFT and KFT Procedure changed to open cholecystectomy Patients on medication like steroids diclofenac optics for chronic pain Abdominal drain will be placed PA requiring any other analgesic other than diclofenac in post operative pain.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the effect on postoperative pain shoulder and abdominal following intraperitoneal instillation of levobupivacaine with three different adjuvants dexmetomidine dexamethasone and magnesium sulphate	Postoperative

Secondary Outcome Measures

Name	Time	Method
To compare the effect of three adjuvants with levobupivacaine on time of first rescue analgesic	Total consumption of rescue analgesic in 24 hours in postoperative period

Trial Locations

Locations (1)

King George Medical College; 🇮🇳 Lucknow, UTTAR PRADESH, India

King George Medical College

🇮🇳Lucknow, UTTAR PRADESH, India

Dr vinod srivastava

Principal investigator

9415795564

vinod123.doctor@gmail.com