Assessment of Hematopoietic Recovery Following Chemotherapy for Non-Hodgkin's Lymphoma

Terminated

• Conditions: Non-Hodgkin's Lymphoma
• Interventions: Procedure: FLT-PET scan; Procedure: FDG-PET scan

• Registration Number: NCT00775957
• Lead Sponsor: University of Oklahoma

Brief Summary

A study to determine the accuracy of FLT-PET in quantifying tumor cell proliferation at the initial staging of patients with Non-Hodgkin's Lymphoma in comparison wit the "gold standard" FDG-PET.

Detailed Description

The first primary objective reflects a necessary and preliminary requirement: to reproduce published results and validate the use of FLT-PET. In this study, 35 patients will be selected to undergoing imaging with both FLT and FDG PET.

Study Timeline

• Study Start: 2008-10
• Study First Submitted: 2008-10-17
• Study First Submitted QC: 2008-10-17
• Study First Posted: 2008-10-20
• Status Verified: 2010-09
• Last Update Submitted: 2010-09-27
• Last Update Posted: 2010-09-28

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• 18 years or older
• Women must not be pregnant or breast feeding
• Histologic diagnosis of non-Hodgkin's lymphoma (any stage)
• Must undergo treatment with chemotherapy and/or radiotherapy

Exclusion Criteria

• May not have received previous therapy with radiopharmaceuticals
• May not have received prior therapy with cytotoxic chemotherapy and/or monoclonal antibodies

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
1	FLT-PET scan	FLT-PET Scan
2	FDG-PET scan	FDG-PET Scan

Primary Outcome Measures

Name	Time	Method
Staging and ReStaging scans	after hematopoetic recovery

Trial Locations

Locations (1)

University of Oklahoma Health Sciences Center; 🇺🇸 Oklahoma City, Oklahoma, United States