FLT-PET/DW-MRI for Detection of Brain Metastases and Early Therapy Evaluation in Patients With Small Cell Lung Cancer

Not Applicable

Completed

• Conditions: Small Cell Lung Cancer
• Interventions: Device: FLT-PET; Device: MRI

• Registration Number: NCT02995902
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

The purpose of the study is to determine the value of FLT-PET early after initiated chemotherapy in patients with small cell lung cancer, and to determine whether MRI of the brain should be performed routinely in these patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-12-11
• Study First Submitted: 2016-12-09
• Study First Submitted QC: 2016-12-16
• Study First Posted: 2016-12-19
• Primary Completion: 2017-02-08
• Study Completion: 2018-02-08
• Status Verified: 2022-05
• Last Update Submitted: 2022-05-03
• Last Update Posted: 2022-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 13

Inclusion Criteria

• biopsy proven small cell lung cancer
• referred for standard chemotherapy
• oral and written informed consent

Exclusion Criteria

• metal or electronical devices in the body not compatible with MRI of brain or thorax
• pregnancy or lactation
• communication difficulties

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
FLT-PET/MRI	FLT-PET	-
FLT-PET/MRI	MRI	-

Primary Outcome Measures

Name	Time	Method
Disease free survival	1 year
Overall survival	1 year

Trial Locations

Locations (1)

Dept. of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet; 🇩🇰 Copenhagen, Denmark