Validation of the French Version of the Primary Lateral Sclerosis Functioning Rating Scale (PLSFRS)
- Conditions
- Lateral Sclerosis
- Registration Number
- NCT06878235
- Lead Sponsor
- University Hospital, Tours
- Brief Summary
This is a national, multicentric, prospective, descriptive study evaluating the psychometric properties of the French version PLSFRS scale
- Detailed Description
This is a prospective study conducted in 8 French ALS centers which will enroll 80 patients with PLS. All these patients will undergo an evaluation of their functional status from the ALSFRS-r and PLSFRS scales. All patients will be evaluated at 3 time points (T0,M6 at the outpatient clinic) and at M3 remotely. The aim of the study will be to validate a trans-cultural and psychometric version of the PLSFRS available for the French PLS population.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 80
- Patients with primary lateral sclerosis (PLS)
- Age over 18 years
- Informed consent signed
- Patients cared in a French ALS centre
- patients with no oral and written command of the French language
- Patients unable to answer a questionnaire
- Opposition to data processing
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method French version of the PLSFRS scale inclusion and 6 months 10 items with a score from 0 to 6; 2 items with a score from 0 to 4 Maximal score is 68.
- Secondary Outcome Measures
Name Time Method Change Global Impression (CGI) scale 6 months overall clinical impression of the change; score from 1 to 7
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
Trial Locations
- Locations (2)
University hospital
🇫🇷Tours, France
University Hospital
🇫🇷Nice, France