DRKS00023440CompletedPhase 4
PROPHYLACTIC INTRAVENOUS KETAMINE, ONDANSETRON AND PETHIDINE IN PREVENTING PERIOPERATIVE SHIVERING IN PATIENTS UNDERGOING ELECTIVE KNEE REPLACEMENT SURGERY UNDER SPINAL ANAESTHESIA: A RANDOMIZED PARALLEL-GROUP, PLACEBO CONTROLLED COMPARATIVE STUDY.
Army Hospital R&R Delhi India0 sites216 target enrollmentStarted: November 2, 2020Last updated:
Conditions
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Enrollment
- 216
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized controlled study
- Masking
- Open (masking not used)
Eligibility Criteria
- Ages
- 18 Years to 75 Years (—)
- Sex
- All
Inclusion Criteria
- •American Society of Anesthesiologists (ASA) physical status I or II], aged (18-75 years), scheduled for Total Knee Replacement surgical operations under spinal anesthesia
Exclusion Criteria
- •2.Exclusion Criteria included patient refusal, ASA Grade > 2, Contraindications to spinal anesthesia, bleeding disorder, thyroid disease, Addison’s disease, Parkinson’s disease, Raynaud’s syndrome. History of convulsions/epilepsy, bronchial asthma, allergy to the agents to be used, blood transfusion during surgery, initial axillary temperature <36.0 or >37.5 °C , use of sedative-hypnotic agents, vasodilators, antidepressants therapy with selective serotonin reuptake inhibitors and monoamine oxidase inhibitors, benzodiazepines. or patients having inadequate Sub arachnoid blockade requiring supplementation by general anaesthesia
Investigators
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