Assessment of Ventriculo-arterial Coupling Characteristics in Sepsis Patients Undergoing Fluid Resuscitation Through Stroke Volume and Calculated End-systolic Pressure interactio

Completed

• Conditions: Patients with septic shock undergo fluid bolus; Ventriculo-arterial Coupling, Arterial Elastance, End-systolic pressure, stroke volume, Septic shock, Fluid resuscitation, Atrial fibrillation

• Registration Number: TCTR20240320006
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2024-02-01
• Study Start: 2024-03-20
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 164

Inclusion Criteria

aged 18 years and older who presented with newly developed sepsis and were transferred to the MICU following participation in three prior prospective studies

Exclusion Criteria

pregnancy, increased intra-abdominal pressure, deep venous thrombosis, significant intra-abdominal masses, pulmonary edema, cardiac failure, brain edema, contraindications for arterial catheter placement, and contraindications for pulse contour cardiac output monitoring

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pes-SV interaction 1 h after intervention Percentage of number of patients who had change in Pes and SV after fluid bolus

Secondary Outcome Measures

Name	Time	Method
subgroups 1 h after intervention Percentage of number of patients who had change in Pes and SV after fluid bolus