EFFECT OF PHYSIOLOGICAL PACING IN RHEUMATIC ATRIAL FIBRILLATION REGISTRY
Not Applicable
- Conditions
- Health Condition 1: I051- Rheumatic mitral insufficiency
- Registration Number
- CTRI/2020/06/025550
- Lead Sponsor
- AIG HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
RHD patients with symptomatic long standing persistent atrial fibrillation in the age group of >= 18years with LA diameter of more than 4.5 cm in heart failure with NYHA functional class >= II, despite optimal medical therapy will be included in the study.
Exclusion Criteria
1-Severe valvular lesions requiring surgery or intervention
2- Significant Coronary artery disease
3-Ongoing infection
4-Pregnancy
5-Severe co-morbidies limiting life expectancy
6-Untreated hypothyroidism, hyperthyroidism
7-Mental or physical inability to participate in the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study improvement in exercise capacity as measured by 6-minute walk test distance (6MWT) following HBP/LBBAP with AVJ ablation <br/ ><br> <br/ ><br>Timepoint: 3 MONTHS
- Secondary Outcome Measures
Name Time Method 1)To Study change in functional class before and after HBP/LBBAP with AVJ ablation.2)To study improvement in cardiac biomarker NT-proBNP3months after HBP/LBBAP and AVJ ablation.3)To study number of heart failure related hospital admissions following HBP/LBBAP and AVJ ablation.4)To study improvement in left ventricular ejection fraction(modified Simpsonâ??s method)/pulmonary artery systolic pressure (PASP)/tricuspid regurgitation/Mitral regurgitation after HBP/LBP and AVJ ablation.Timepoint: 3 MONTHS