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Clinical Trials/NCT04289311
NCT04289311
Completed
Not Applicable

SMYLS: A Self-management Program for Youth Living With Sickle Cell Disease

Medical University of South Carolina1 site in 1 country30 target enrollmentJuly 13, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sickle Cell Disease
Sponsor
Medical University of South Carolina
Enrollment
30
Locations
1
Primary Endpoint
Consistency of Intervention Delivery
Status
Completed
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to find out whether a web-based intervention using a mobile device is helpful for teens learning to care for and manage symptoms of sickle cell disease. The intervention lasts 12 weeks with a 3-month follow up period, and uses a smartphone or a tablet.

Detailed Description

The purpose of the proposed study is to test the feasibility of SMYLS, an mHealth intervention designed to facilitate self-management behaviors in children and adolescents with sickle cell disease (SCD). Specifically, the investigators propose to test the feasibility of the intervention for improving transition from parent-managed to adolescent self-managed care. In addition, the investigators will evaluate the communication that takes place via the intervention between adolescents, their parents/caregivers, and healthcare providers. The investigators will work with the MUSC Pediatric Sickle Cell Clinic to identify and recruit 5 healthcare providers of children with SCD and 30 dyads of adolescents ages 11 - 17 SCD and their parent/caregiver (n = 60).

Registry
clinicaltrials.gov
Start Date
July 13, 2020
End Date
December 17, 2021
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Shannon Phillips

Associate Professor

Medical University of South Carolina

Eligibility Criteria

Inclusion Criteria

  • diagnosis of SCD as reported by provider
  • self-reported history of pain at least once per month
  • caregiver/parent willingness to participate
  • owns a smartphone

Exclusion Criteria

  • not under the care of a provider participant
  • cognitive disability or delay that precludes ability to participate, defined as classified severe neurocognitive deficits as documented by neuropsychological evaluation in the medical record
  • lack of wi-fi access

Outcomes

Primary Outcomes

Consistency of Intervention Delivery

Time Frame: 24 weeks

Number of participants (adolescent/caregiver dyads and young adults) to whom instructions on the intervention were provided as recorded in study logs

Rate of Recruitment: Dyads

Time Frame: 6 months

Number of participant dyads recruited and enrolled per week. (Benchmark is 2 dyads recruited and enrolled per week to reach sample size of 30 dyads)

Participant Adherence to the Intervention

Time Frame: baseline to 6 weeks

Number of participants (adolescent/caregiver dyads and young adults) using the app from baseline to 6 weeks

Projection of Future Adoption

Time Frame: 12 weeks

Number of participants (adolescent/caregiver dyads and individual young adults) who report they are likely or very likely to continue using the intervention during post-intervention, semi-structured interviews

Participant (Adolescent/Caregiver Dyads and Young Adults) Adherence to the Intervention From 6 Weeks to 12 Weeks

Time Frame: 6 weeks to 12 weeks

Number of participants (adolescent/caregiver dyads and young adults) who used the intervention from week 6 to week 12

Participant (Adolescent/Caregiver Dyads and Young Adults) Adherence to the Intervention From 12 Weeks to 24 Weeks

Time Frame: 12 weeks to 24 weeks

Number of participants (adolescent/caregiver dyads and young adults) who used the intervention from week 12 to week 24

Rate of Recruitment: Young Adults

Time Frame: 6 months

Number of young adult participants recruited and enrolled per week. (Benchmark is 2 young adults recruited per week to reach a sample size of 15).

Secondary Outcomes

  • Difference in Mean Scores for Anxiety From Baseline to End-of-Intervention(baseline, 12 weeks)
  • Difference in Mean Scores for Fatigue From Baseline to End-of-Intervention(baseline, 12 weeks)
  • Difference in Mean Scores for Self-Efficacy From Baseline to End-of-Intervention(baseline, 12 weeks)
  • Differences in Mean Scores on Depressive Symptoms From Baseline to End-of-Intervention(baseline, 12 weeks)
  • Differences in Mean Scores for Pain Intensity From Baseline to End-of-interention(baseline, 12 weeks)
  • Difference in Mean Pain Score Rating From Baseline to End-of-Intervention(baseline, 12 weeks)
  • Difference in Mean Scores for Transition Readiness From Baseline to End-of-intervention(baseline, 12 weeks)
  • Differences in Mean Scores for Condition-Specific Quality of Life From Baseline to End-of-Intervention(baseline, 12 weeks)
  • Differences in Mean Scores for Quality of Life From Baseline to End-of-Intervention(baseline, 12 weeks)

Study Sites (1)

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