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Clinical Trials/NCT06035939
NCT06035939
Recruiting
Not Applicable

Self-Management for Youth Living With Sickle Cell Disease: SMYLS Multi-site Trial

Medical University of South Carolina1 site in 1 country272 target enrollmentApril 4, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sickle Cell Disease
Sponsor
Medical University of South Carolina
Enrollment
272
Locations
1
Primary Endpoint
Self-management behaviors
Status
Recruiting
Last Updated
4 months ago

Overview

Brief Summary

The purpose of this study is to find out whether a web-based intervention using a mobile app is helpful for teens and young adults with sickle cell disease (SCD) in learning how to care for and manage their symptoms.

Detailed Description

The purpose of this study is to test the effectiveness of and identify barriers and facilitators to the implementation of SMYLS, an mHealth intervention designed to facilitate self-management behaviors in adolescents and young adults (AYA) with sickle cell disease (SCD). Specifically, the investigators propose to determine the effect of the intervention on the primary outcome of self-management behaviors and the secondary outcomes of quality of life, transition readiness, healthcare utilization, and pain interference. In addition, the investigators will explore how patient activation moderates development of self-management behaviors and systemic, structural, and social variables that moderate relationships between patient activation, the primary outcome, and secondary outcomes.

Registry
clinicaltrials.gov
Start Date
April 4, 2024
End Date
January 31, 2028
Last Updated
4 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Shannon Phillips

Associate Professor-Faculty

Medical University of South Carolina

Eligibility Criteria

Inclusion Criteria

  • documentation in the electronic health record of any type of SCD
  • owns mobile device compatible with the intervention
  • access to the internet

Exclusion Criteria

  • Plans to relocate outside of study site area in the next 12 months
  • Plans to transition to adult care in 12 months or less
  • Parent/caregiver or provider report of neurocognitive impairment that precludes ability to use intervention and participate in study
  • non-English speaking

Outcomes

Primary Outcomes

Self-management behaviors

Time Frame: baseline and 1, 3, 6, 9, 12 months

Adolescent and young adult self-report using the Transition Readiness Assessment Questionnaire 5th version (TRAQ-5; 20 items). The instrument consists of 5 scales. Individual item scores range from 1 - 5. Scale scores are determined by calculating the average of the item scores within each scale. Higher scores indicate greater transition readiness and self-management behaviors.

Secondary Outcomes

  • Transition readiness(baseline and 1, 3, 6, 9, and 12 months)
  • Number of hospitalizations(baseline and 1, 3, 6, 9, and 12 months)
  • Engagement in intervention/control (categorical)(baseline and 1, 3, 6, 9, 12 months)
  • Number of ED visits(baseline and 1, 3, 6, 9, and 12 months)
  • Number of attended SCD clinic visits(baseline and 1, 3, 6, 9, and 12 months)
  • Pain interference(baseline and 1, 3, 6, 9, and 12, months)
  • Engagement in intervention/control (continuous)(Ongoing)
  • Health-related quality of life(baseline and 1, 3, 6, 9, and 12 months)

Study Sites (1)

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