Effects of mobilization with movement vs Maitland joint mobilization as an adjunct to institution-based exercise program on pain, ROM, strength, functional status & quality of life in knee osteoarthritis patients: A randomised clinical trial
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- 1.VAS (Pain)
研究概览
简要总结
Knee osteoarthritis is an articular degenerative disease. It is a complex joint condition that affects the entire joint, including bone, cartilage, synovium, ligaments and joint capsule. Symptoms of knee osteoarthritis include pain, joint stiffness, muscular weakness, poor proprioception and limited joint motion affecting daily life activities. The management of knee osteoarthritis aims to control pain, while improving physical function and quality of life. The OARSI, ACR and EULAR clinical practice guidelines promote an active lifestyle in osteoarthritis patients and states that exercise program aimed at improving cardiopulmonary fitness, muscular strength, flexibility and neuromuscular performance should be integrated into therapeutic management. Manual therapy has been used as a part of multimodal rehabilitation management for knee osteoarthritis because of its ability to relieve symptoms. For individuals with symptomatic knee osteoarthritis, adding manual therapy treatment in the form of mobilization with movement or Maitland joint mobilization to the baseline exercise program delivers advantages beyond what the same exercises alone may provide. Maitland concept is a patient driven model of passive joint mobilization, where passive oscillatory movements are performed at the limit of the range. Whereas, Mulligan’s mobilization with movement is a relatively new concept that utilises pain-free low-velocity joint mobilization techniques that can include an active movement component. Manual therapy appears to be effective in relieving symptoms but the effects on pain, joint motion, strength, physical functions and quality of life is still needed to be further explored. There are sufficient evidences for use of manual therapy techniques like mobilization with movement and Maitland joint mobilization in knee osteoarthritis patients but the comparison of the effects of these manual therapy techniques is still controversial. Thus, this study aims to compare the effects of mobilization with movement and Maitland joint mobilization using outcome measure VAS, Universal Goniometer, MicroFET3, TUG, 30s chair stand test, WOMAC CRD Pune and WHOQOL-BREF in knee osteoarthritis patients.
Null hypothesis- mobilization with movement and Maitland joint mobilization will be equally effective as an adjunct to institution-based exercise program on pain, Rom, strength, functional status & quality of life in knee osteoarthritis patients.
Alternative hypothesis 1- mobilization with movement will have better effects than Maitland joint mobilization as an adjunct to institution-based exercise program on pain, ROM, strength, functional status & quality of life in knee osteoarthritis patients.
Alternative hypothesis 2- Maitland joint mobilization will have better effects than mobilization with movement as an adjunct to institution-based exercise program on pain, ROM, strength, functional status & quality of life in knee osteoarthritis patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 75.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Subjects of either gender with an age group of 40-75yrs & having knee pain.
- •2.Subjects fulfilling American College of Rheumatology clinical criteria.
- •At least one of the following three Age more than 50, morning stiffness less than 30 min, Crepitus on knee motion, with or without X Ray findings.
- •3.Subjects with grade I to III knee osteoarthritis on the Kellgren and Lawrence scale.
- •4.Subjects able to stand and walk without help.
排除标准
- •1.Subjects with history of knee/ lower limb joint replacement surgery.
- •2.Subjects present with history of any lower limb fracture or ligament injury.
- •3.Subjects with post-traumatic knee osteoarthritis.
- •4.Subjects with patellofemoral arthritis.
结局指标
主要结局
1.VAS (Pain)
时间窗: At baseline (0 weeks) and | Post-intervention (4 weeks)
2.Universal goniometer
时间窗: At baseline (0 weeks) and | Post-intervention (4 weeks)
次要结局
- Time up and go(At baseline (0 weeks) and)
- 30s chair stand test(At baseline (0 weeks) and)
- WOMAC CRD Pune(At baseline (0 weeks) and)
- Micro FET3(At baseline (0 weeks) and)
- WHOQOL-BREF(At baseline (0 weeks) and)
研究者
Vedangi Sudhir Trikande
Sancheti Institute for orthopaedics and Rehabilitation College of Physiotherapy