Dexmedetomidine Combined With Bupivacaine for Erector Spinae Plane Block
Phase 1
Completed
- Conditions
- Posterior Lumbosacral Spine Fixation Surgeries
- Interventions
- Registration Number
- NCT05590234
- Lead Sponsor
- October 6 University
- Brief Summary
As the posterior lumbosacral spine fixation surgeries are common spine procedures done nowadays due to different causes and as this spine procedure is mostly accompanied with moderate to severe postoperative pain, so it is necessary to find an effective and efficient postoperative analgesia for patients with this surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
- elective posterior lumbosacral spine fixation and fusion surgery due to different causes that diagnosed clinically and radiologically including MRI and Plain X ray
Exclusion Criteria
- hypersensitivity to the drugs used in the study [local anesthetics, non-steroidal anti-inflammatory drugs, opioids and the drug under investigation (dexmedetomidine)]
- patients with any contraindication to regional anesthesia as skin infections at the site of the block
- history of bleeding disorders or receiving anticoagulant medications
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Dexmedetomidine combined with bupivacaine group (DB group) Dexmedetomidine injection patients received 1ug/kg dexmedetomidine plus 20 mL of bupivacaine 0.25%, Dexmedetomidine combined with bupivacaine group (DB group) Bupivacaine 0.25% Injectable Solution patients received 1ug/kg dexmedetomidine plus 20 mL of bupivacaine 0.25%, control group (S group) normal saline patients received 20 ml of normal saline 0.9%. bupivacaine 0.25%, Bupivacaine 0.25% Injectable Solution patients received 20 ml of bupivacaine 0.25%
- Primary Outcome Measures
Name Time Method Postoperative visual analogue scale (VAS) the first 24 hours postoperative The visual analog scale (VAS) is a simple and often used method for evaluating variations in pain intensity.
Amount of post operative opioid consumption for the first 24 hours the first 24 hours postoperative Amount of total opioid consumption for 24 hours postoperative
- Secondary Outcome Measures
Name Time Method Postoperative visual analogue scale (VAS) the second 24 hour postoperative The visual analog scale (VAS) is a simple and often used method for evaluating variations in pain intensity.
Amount of post operative opioid consumption for the second 24 hours the second 24 hour postoperative Amount of total opioid consumption for the second 24 hours postoperative
Trial Locations
- Locations (1)
October 6 university hospital
🇪🇬Giza, Egypt