Effect of Dexmedetomidine on Outcomes During Emergence From Retroperitoneal Laparoscopic Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- Richmond Score
研究概览
简要总结
The study is to observe whether dexmedetomidine could reduce agitation during emergence from general anesthesia in patients undergoing retroperitoneal laparoscopic surgery.
详细描述
Agitation during emergence is frequent after retroperitoneal urologic surgery. Dexmedetomidine is alpha-2 receptor agonist which shows sedative and algesic effect. In this study we will compare the effect of dexmedetomidine given by different protocols on emergence agitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for retroperitoneal laparoscopic surgery
- •Patients with written informed consent
排除标准
- •Patients with difficulty of communication
- •Patients with risk of obstructive sleeping apnea syndrome
研究组 & 干预措施
dexmedetomidine loading dose
dexmedetomidine is given at load dose
干预措施: dexmedetomidine (Drug)
dexmedetomidine loading dose
dexmedetomidine is given at load dose
干预措施: loading dose (Other)
dexmedetomidine sustaining dose
dexmedetomidine is given at sustaining dose
干预措施: dexmedetomidine (Drug)
dexmedetomidine sustaining dose
dexmedetomidine is given at sustaining dose
干预措施: sustaining dose (Other)
结局指标
主要结局
Richmond Score
时间窗: From end of sevoflurane inhalation to departure from PACU, an expected average of 1 hour
次要结局
- Time to awake(From end of sevoflurane inhalation to departure from PACU, an expected average of 1 hour)
- Cough score(From end of sevoflurane inhalation to departure from PACU, an expected average of 1 hour)
研究者
Zhihong LU
Dr
Air Force Military Medical University, China