Consequence of Dexmedetomidine on Emergence Deliruim After Sevoflurane Anesthesia in Children With Cerebral Palsy

Jin Ni0 sites80 target enrollmentJune 2014

ConditionsEmergence Deliruim; Cerebral Palsy

Interventionsdexmedetomidine

Drugsdexmedetomidine

Overview

Phase: Phase 4
Intervention: dexmedetomidine
Conditions: Emergence Deliruim; Cerebral Palsy
Sponsor: Jin Ni
Enrollment: 80
Primary Endpoint: Heart rate
Last Updated: 11 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Similar Trials

Overview

Brief Summary

The purpose of this study is to determine whether dexmedetomidine is effective in the treatment of emergence deliruim after sevoflurane anesthesia in children with cerebral palsy.

Registry

clinicaltrials.gov

Start Date

June 2014

End Date

September 2014

Last Updated

11 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Jin Ni

Responsible Party

Sponsor Investigator

Principal Investigator

Jin Ni

Vice-administrator of Department of Anesthesiology

Guangzhou Women and Children's Medical Center

Eligibility Criteria

Inclusion Criteria

•Non-quadriplegic (mono-,di-, hemiplegic) children with CP that are scheduled for elective Achilles-tendon lengthening procedure Guangzhou Women and Children's Medical Center, Guangzhou, China, with American Society of Anesthesiologists (ASA) physical status I or II.

Exclusion Criteria

•Participants that displayed symptoms of sinus bradycardia and atrio-ventricular block, non-communicative severe developmental delay, seizure disorders, and treatment with seizure medications

Arms & Interventions

Group D

Five minutes prior to the commencement of the surgical procedure, Group D participants were administered dexmedetomidine 0.5μg•kg-1 diluted in 10 ml NaCI 0.9%

Intervention: dexmedetomidine